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David Shum

  1. "Hakim Djaballah"
Formats
  1. Journal Article (34)
  2. Meeting Abstract (19)
Groups
  1. GSK Faculty (25)
  2. Center for Hematologic Malignancies (20)
  3. Adult Leukemia (16)
  4. Department of Medicine (16)
  5. Hematologic Malignancies Research (16)
  6. Hematologic Malignancies, Division of (15)

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People
  1. Hakim Djaballah (53)
  2. Constantin Radu (22)
  3. Bhavneet Bhinder (19)
  4. Christophe Antczak (13)
  5. Mark Frattini (13)
  6. Renier Brentjens (8)

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Years
  1. 2023 (1)
  2. 2022 (1)
  3. 2018 (1)
  4. 2016 (1)
  5. 2015 (2)
  6. 2014 (10)

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Publications
  1. Cancer Research (9)
  2. Combinatorial Chemistry and High Throughput Screening (9)
  3. Assay and Drug Development Technologies (7)
  4. Blood (5)
  5. Clinical Cancer Research (3)
  6. Journal of Biomolecular Screening (3)

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Publishers
  1. American Association for Cancer Research (12)
  2. Bentham Science Publishers (9)
  3. Mary Ann Liebert, Inc (8)
  4. American Society of Hematology (5)
  5. Sage Publications (4)
  6. Elsevier Inc. (3)

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Results (53)

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  • A genome-wide RNAi screen reveals common host-virus gene signatures: Implication for dengue antiviral drug discovery
    Journal Article

    Shum, D.; Bhinder, B.; Mahida, J.; Radu, C.; Calder, P. A.; Djaballah, H.
    Gen Biotechnology (2023)

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  • A high-content screen for C/EBPα expression identifies novel therapeutic agents in dedifferentiated liposarcoma
    Journal Article

    Angeles, C. V.; Velez, A.; Rios, J.; Laxa, B.; Shum, D.; Ruiz, P. D.; Shen, Y.; Ostrovnaya, I.; Gularte-Mérida, R.; Nacev, B. A.; more...
    Clinical Cancer Research (2022)

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  • Evaluation of compound optical interference in high-content screening
    Journal Article

    Ibáñez, G.; Calder, P. A.; Radu, C.; Bhinder, B.; Shum, D.; Antczak, C.; Djaballah, H.
    SLAS Discovery (2018)

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  • Proteasome addiction defined in Ewing sarcoma is effectively targeted by a novel class of 19S proteasome inhibitors
    Journal Article

    Shukla, N.; Somwar, R.; Smith, R. S.; Ambati, S.; Munoz, S.; Merchant, M.; D'Arcy, P.; Wang, X.; Kobos, R.; Antczak, C.; more...
    Cancer Research (2016)

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  • A novel high-throughput screen of primary leukemia cells to personalize therapy for relapsed/refractory acute myeloid leukemia (AML): Proof of concept and clinical implementation of precision medicine
    Meeting Abstract

    Shum, D.; Santos, R.; Heaney, M.; Brentjens, R.; Maslak, P.; Rosenblat, T.; Jurcic, J.; Djaballah, H.; Frattini, M. G.
    Clinical Cancer Research (2015)

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  • Use of a high-throughput screen of primary leukemia cells to personalize therapy for relapsed/refractory AML: Proof of concept and clinical implementation of precision medicine
    Meeting Abstract

    Shum, D.; Heaney, M.; Brentjens, R.; Maslak, P.; Jurcic, J.; Djaballah, H.; Frattini, M. G.
    Clinical Cancer Research (2015)

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  • A phase I trial of a pharmacodynamically-conceived decitabine and thioguanine combination in patients with advanced myeloid malignancies
    Meeting Abstract

    Rosenblat, T.; Heaney, M. L.; Jurcic, J. G.; Raza, A.; Mears, J. G.; Santos, R.; Carrillo, D.; Shum, D.; Gonzales, J.; Zikaras, K.; more...
    Blood (2014)

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  • Targeting the cell cycle regulated CDC7 kinase pathway as a novel therapeutic approach for hematologic malignancies
    Meeting Abstract

    Santos, R.; Shum, D.; Churchill, M.; Mukherjee, S.; Brentjens, R. J.; Jurcic, J. G.; Kelly, T.; Djaballah, H.; Frattini, M. G.
    Clinical Lymphoma, Myeloma and Leukemia (2014)

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  • Inhibition of the cell cycle regulated Cdc7 kinase pathway is an efficacious therapeutic approach for hematologic malignancies and solid tumors
    Meeting Abstract

    Santos, R.; Shum, D.; Carrillo, D.; Zhang, R.; Churchill, M.; Mukherjee, S.; Brentjens, R.; Radu, C.; Kelly, T. J.; Djaballah, H.; more...
    European Journal of Cancer (2014)

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  • Small-molecule inhibitors of setd8 with cellular activity
    Journal Article

    Blum, G.; Ibáñez, G.; Rao, X.; Shum, D.; Radu, C.; Djaballah, H.; Rice, J. C.; Luo, M.
    ACS Chemical Biology (2014)

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