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David Shum

  1. "Hematologic Malignancies, Division of"
Formats
  1. Meeting Abstract (10)
  2. Journal Article (5)
Groups
  1. Department of Medicine (15)
  2. Hematologic Malignancies, Division of (15)
  3. Adult Leukemia (14)
  4. Center for Hematologic Malignancies (14)
  5. GSK Faculty (14)
  6. Hematologic Malignancies Research (13)

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People
  1. Hakim Djaballah (15)
  2. Renier Brentjens (8)
  3. Mark Frattini (7)
  4. Peter Maslak (6)
  5. David Scheinberg (5)
  6. Thomas Kelly (5)

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Years
  1. 2015 (2)
  2. 2014 (2)
  3. 2012 (1)
  4. 2011 (1)
  5. 2010 (2)
  6. 2009 (5)

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Publications
  1. Blood (3)
  2. Cancer Research (3)
  3. Assay and Drug Development Technologies (2)
  4. Bioorganic & Medicinal Chemistry Letters (2)
  5. Clinical Cancer Research (2)
  6. Clinical Lymphoma, Myeloma and Leukemia (1)

More Publications

Publishers
  1. American Association for Cancer Research (5)
  2. American Society of Hematology (3)
  3. Elsevier Inc. (2)
  4. Mary Ann Liebert, Inc (2)
  5. Pergamon-Elsevier Science Ltd (2)
  6. Sage Publications (1)

Results (15)

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  • A novel high-throughput screen of primary leukemia cells to personalize therapy for relapsed/refractory acute myeloid leukemia (AML): Proof of concept and clinical implementation of precision medicine
    Meeting Abstract

    Shum, D.; Santos, R.; Heaney, M.; Brentjens, R.; Maslak, P.; Rosenblat, T.; Jurcic, J.; Djaballah, H.; Frattini, M. G.
    Clinical Cancer Research (2015)

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  • Use of a high-throughput screen of primary leukemia cells to personalize therapy for relapsed/refractory AML: Proof of concept and clinical implementation of precision medicine
    Meeting Abstract

    Shum, D.; Heaney, M.; Brentjens, R.; Maslak, P.; Jurcic, J.; Djaballah, H.; Frattini, M. G.
    Clinical Cancer Research (2015)

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  • Targeting the cell cycle regulated CDC7 kinase pathway as a novel therapeutic approach for hematologic malignancies
    Meeting Abstract

    Santos, R.; Shum, D.; Churchill, M.; Mukherjee, S.; Brentjens, R. J.; Jurcic, J. G.; Kelly, T.; Djaballah, H.; Frattini, M. G.
    Clinical Lymphoma, Myeloma and Leukemia (2014)

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  • Inhibition of the cell cycle regulated Cdc7 kinase pathway is an efficacious therapeutic approach for hematologic malignancies and solid tumors
    Meeting Abstract

    Santos, R.; Shum, D.; Carrillo, D.; Zhang, R.; Churchill, M.; Mukherjee, S.; Brentjens, R.; Radu, C.; Kelly, T. J.; Djaballah, H.; more...
    European Journal of Cancer (2014)

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  • A high-throughput scintillation proximity-based assay for human DNA ligase IV
    Journal Article

    Tseng, H. M.; Shum, D.; Bhinder, B.; Escobar, S.; Veomett, N. J.; Tomkinson, A. E.; Gin, D. Y.; Djaballah, H.; Scheinberg, D. A.
    Assay and Drug Development Technologies (2012)

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  • Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase
    Journal Article

    Antczak, C.; Shum, D.; Bassit, B.; Frattini, M. G.; Li, Y.; de Stanchina, E.; Scheinberg, D. A.; Djaballah, H.
    Bioorganic & Medicinal Chemistry Letters (2011)

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  • Identification of DNA ligase IV inhibitors as possible drug and probe candidates for enhancement of radiation treatment and chemotherapy
    Meeting Abstract

    Tseng, H. M.; Shum, D.; Djaballah, H.; Scheinberg, D.
    Cancer Research (2010)

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  • A high-throughput screen for alpha particle radiation protectants
    Journal Article

    Seideman, J. H.; Shum, D.; Djaballah, H.; Scheinberg, D. A.
    Assay and Drug Development Technologies (2010)

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  • Discovery and validation of a novel class of small molecule inhibitors of the CDC7 kinase: Modulation of tumor cell growth in vitro and in vivo
    Meeting Abstract

    Frattini, M. G.; Shum, D.; O'Dwyer, K. M.; Brentjens, R. J.; Maslak, P.; Heaney, M.; Jurcic, J. G.; Djaballah, H.; Kelly, T. J.
    Blood (2009)

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  • Clinical implementation of a novel high-throughput screen of primary leukemia cells to customize therapy for relapsed/refractory acute myeloid leukemia (AML)
    Meeting Abstract

    O'Dwyer, K. M.; Shum, D.; Heaney, M.; Brentjens, R. J.; Maslak, P.; Jurcic, J. G.; Djaballah, H.; Frattini, M. G.
    Blood (2009)

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