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David Shum

  1. "GSK Faculty"
Formats
  1. Meeting Abstract (13)
  2. Journal Article (12)
Groups
  1. GSK Faculty (25)
  2. Center for Hematologic Malignancies (18)
  3. Hematologic Malignancies Research (16)
  4. Department of Medicine (15)
  5. Adult Leukemia (14)
  6. Hematologic Malignancies, Division of (14)

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People
  1. Hakim Djaballah (25)
  2. Renier Brentjens (8)
  3. Constantin Radu (7)
  4. Mark Frattini (7)
  5. Christophe Antczak (6)
  6. Peter Maslak (6)

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Years
  1. 2022 (1)
  2. 2016 (1)
  3. 2015 (2)
  4. 2014 (4)
  5. 2013 (1)
  6. 2012 (2)

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Publications
  1. Cancer Research (5)
  2. Assay and Drug Development Technologies (3)
  3. Blood (3)
  4. Clinical Cancer Research (3)
  5. Combinatorial Chemistry and High Throughput Screening (3)
  6. ACS Chemical Biology (1)

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Publishers
  1. American Association for Cancer Research (8)
  2. American Society of Hematology (3)
  3. Bentham Science Publishers (3)
  4. Mary Ann Liebert, Inc (3)
  5. Elsevier Inc. (2)
  6. American Chemical Society (1)

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Results (25)

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  • Discovery and validation of a novel class of small molecule inhibitors of the Cdc7 kinase: Modulation of tumor cell growth in vitro and in vivo
    Meeting Abstract

    Frattini, M. G.; Shum, D.; O'dwyer, K. M.; Brentjens, R. J.; Yeh, R.; Maslak, P. G.; Djaballah, H.; Kelly, T. J.
    Cancer Research (2009)

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  • A miniaturized 1536-well format γ-secretase assay
    Journal Article

    Shelton, C. C.; Tian, Y.; Shum, D.; Radu, C.; Djaballah, H.; Li, Y. M.
    Assay and Drug Development Technologies (2009)

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  • Small molecule inhibition of Cdc7, a key cell cycle regulator and novel therapeutic target, successfully inhibits leukemia cell growth in vitro and in vivo
    Meeting Abstract

    Frattini, M. G.; Shum, D.; O'dwyer, K. M.; Brentjens, R. J.; Yeh, R.; Maslak, P.; Heaney, M. L.; Jurcic, J.; Djaballah, H.; Kelly, T. J.
    Blood (2008)

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  • High-throughput identification of inhibitors of human mitochondrial peptide deformylase
    Journal Article

    Antczak, C.; Shum, D.; Escobar, S.; Bassit, B.; Kim, E.; Seshan, V. E.; Wu, N.; Yang, G.; Ouerfelli, O.; Li, Y. M.; more...
    Journal of Biomolecular Screening (2007)

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  • High throughput profiling of leukemia and lymphoma cell lines using small molecules: In search of conserved and novel chemical scaffold signatures effective for specific diseases
    Meeting Abstract

    Frattini, M. G.; Shum, D.; Santos, R.; Ahmed, A.; Djaballah, H.; Kelly, T. J.
    Cancer Research (2006)

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