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David Shum

  1. "GSK Faculty"
Formats
  1. Meeting Abstract (13)
  2. Journal Article (12)
Groups
  1. GSK Faculty (25)
  2. Center for Hematologic Malignancies (18)
  3. Hematologic Malignancies Research (16)
  4. Department of Medicine (15)
  5. Adult Leukemia (14)
  6. Hematologic Malignancies, Division of (14)

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People
  1. Hakim Djaballah (25)
  2. Renier Brentjens (8)
  3. Constantin Radu (7)
  4. Mark Frattini (7)
  5. Christophe Antczak (6)
  6. Peter Maslak (6)

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Years
  1. 2022 (1)
  2. 2016 (1)
  3. 2015 (2)
  4. 2014 (4)
  5. 2013 (1)
  6. 2012 (2)

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Publications
  1. Cancer Research (5)
  2. Assay and Drug Development Technologies (3)
  3. Blood (3)
  4. Clinical Cancer Research (3)
  5. Combinatorial Chemistry and High Throughput Screening (3)
  6. ACS Chemical Biology (1)

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Publishers
  1. American Association for Cancer Research (8)
  2. American Society of Hematology (3)
  3. Bentham Science Publishers (3)
  4. Mary Ann Liebert, Inc (3)
  5. Elsevier Inc. (2)
  6. American Chemical Society (1)

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Results (25)

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  • A high throughput scintillation proximity imaging assay for protein methyltransferases
    Journal Article

    Ibáñez, G.; Shum, D.; Blum, G.; Bhinder, B.; Radu, C.; Antczak, C.; Luo, M.; Djaballah, H.
    Combinatorial Chemistry and High Throughput Screening (2012)

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  • Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines
    Journal Article

    Somwar, R.; Erdjument-Bromage, H.; Larsson, E.; Shum, D.; Lockwood, W. W.; Yang, G.; Sander, C.; Ouerfelli, O.; Tempst, P. J.; Djaballah, H.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2011)

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  • Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase
    Journal Article

    Antczak, C.; Shum, D.; Bassit, B.; Frattini, M. G.; Li, Y.; de Stanchina, E.; Scheinberg, D. A.; Djaballah, H.
    Bioorganic & Medicinal Chemistry Letters (2011)

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  • Identification of selective inhibitors of dedifferentiated liposarcoma cells by high-throughput screening (HTS)
    Meeting Abstract

    Angeles, C. V.; Laxa, B.; Shum, D.; DeCarolis, P.; Gobble, R.; Brill, E.; Ugras, S.; O'Connor, R.; Djaballah, H.; Singer, S.
    Journal of Clinical Oncology (2010)

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  • Identification of DNA ligase IV inhibitors as possible drug and probe candidates for enhancement of radiation treatment and chemotherapy
    Meeting Abstract

    Tseng, H. M.; Shum, D.; Djaballah, H.; Scheinberg, D.
    Cancer Research (2010)

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  • SN-38 is a potential targeted chemotherapeutic for dedifferentiated liposarcoma
    Meeting Abstract

    Angeles, C. V.; Ugras, S.; Gobble, R. M.; Decarolis, P.; Shum, D.; Ostrovnaya, I.; O'Connor, R.; Djaballah, H.; Schwartz, G. K.; Singer, S.
    Journal of the American College of Surgeons (2010)

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  • A high-throughput screen for alpha particle radiation protectants
    Journal Article

    Seideman, J. H.; Shum, D.; Djaballah, H.; Scheinberg, D. A.
    Assay and Drug Development Technologies (2010)

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  • Discovery and validation of a novel class of small molecule inhibitors of the CDC7 kinase: Modulation of tumor cell growth in vitro and in vivo
    Meeting Abstract

    Frattini, M. G.; Shum, D.; O'Dwyer, K. M.; Brentjens, R. J.; Maslak, P.; Heaney, M.; Jurcic, J. G.; Djaballah, H.; Kelly, T. J.
    Blood (2009)

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  • Clinical implementation of a novel high-throughput screen of primary leukemia cells to customize therapy for relapsed/refractory acute myeloid leukemia (AML)
    Meeting Abstract

    O'Dwyer, K. M.; Shum, D.; Heaney, M.; Brentjens, R. J.; Maslak, P.; Jurcic, J. G.; Djaballah, H.; Frattini, M. G.
    Blood (2009)

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  • The functional analysis of a novel KDR (VEGFR II)-PDGFR-alpha fusion gene in glioblastoma: From discovery to clinical application
    Meeting Abstract

    Ozawa, T.; Brennan, C. W.; Normand, G.; Wang, L.; Antczak, C.; Shum, D.; Tandon, A.; Fomchenko, E.; Squatrito, M.; Levine, R. L.; more...
    Cancer Research (2009)

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