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David Shum

  1. "Center for Hematologic Malignancies"
Formats
  1. Meeting Abstract (12)
  2. Journal Article (8)
Groups
  1. Center for Hematologic Malignancies (20)
  2. GSK Faculty (18)
  3. Adult Leukemia (16)
  4. Hematologic Malignancies Research (16)
  5. Department of Medicine (14)
  6. Hematologic Malignancies, Division of (14)

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People
  1. Hakim Djaballah (20)
  2. Renier Brentjens (8)
  3. Christophe Antczak (6)
  4. Mark Frattini (6)
  5. Peter Maslak (6)
  6. Constantin Radu (5)

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Years
  1. 2016 (1)
  2. 2015 (2)
  3. 2014 (4)
  4. 2012 (2)
  5. 2011 (1)
  6. 2010 (3)

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Publications
  1. Cancer Research (6)
  2. Blood (3)
  3. Assay and Drug Development Technologies (2)
  4. Clinical Cancer Research (2)
  5. Combinatorial Chemistry and High Throughput Screening (2)
  6. ACS Chemical Biology (1)

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Publishers
  1. American Association for Cancer Research (8)
  2. American Society of Hematology (3)
  3. Bentham Science Publishers (2)
  4. Elsevier Inc. (2)
  5. Mary Ann Liebert, Inc (2)
  6. American Chemical Society (1)

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Results (20)

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  • Proteasome addiction defined in Ewing sarcoma is effectively targeted by a novel class of 19S proteasome inhibitors
    Journal Article

    Shukla, N.; Somwar, R.; Smith, R. S.; Ambati, S.; Munoz, S.; Merchant, M.; D'Arcy, P.; Wang, X.; Kobos, R.; Antczak, C.; more...
    Cancer Research (2016)

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  • A novel high-throughput screen of primary leukemia cells to personalize therapy for relapsed/refractory acute myeloid leukemia (AML): Proof of concept and clinical implementation of precision medicine
    Meeting Abstract

    Shum, D.; Santos, R.; Heaney, M.; Brentjens, R.; Maslak, P.; Rosenblat, T.; Jurcic, J.; Djaballah, H.; Frattini, M. G.
    Clinical Cancer Research (2015)

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  • Use of a high-throughput screen of primary leukemia cells to personalize therapy for relapsed/refractory AML: Proof of concept and clinical implementation of precision medicine
    Meeting Abstract

    Shum, D.; Heaney, M.; Brentjens, R.; Maslak, P.; Jurcic, J.; Djaballah, H.; Frattini, M. G.
    Clinical Cancer Research (2015)

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  • Targeting the cell cycle regulated CDC7 kinase pathway as a novel therapeutic approach for hematologic malignancies
    Meeting Abstract

    Santos, R.; Shum, D.; Churchill, M.; Mukherjee, S.; Brentjens, R. J.; Jurcic, J. G.; Kelly, T.; Djaballah, H.; Frattini, M. G.
    Clinical Lymphoma, Myeloma and Leukemia (2014)

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  • Inhibition of the cell cycle regulated Cdc7 kinase pathway is an efficacious therapeutic approach for hematologic malignancies and solid tumors
    Meeting Abstract

    Santos, R.; Shum, D.; Carrillo, D.; Zhang, R.; Churchill, M.; Mukherjee, S.; Brentjens, R.; Radu, C.; Kelly, T. J.; Djaballah, H.; more...
    European Journal of Cancer (2014)

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  • Small-molecule inhibitors of setd8 with cellular activity
    Journal Article

    Blum, G.; Ibáñez, G.; Rao, X.; Shum, D.; Radu, C.; Djaballah, H.; Rice, J. C.; Luo, M.
    ACS Chemical Biology (2014)

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  • A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of rna-binding proteins
    Journal Article

    Minuesa, G.; Antczak, C.; Shum, D.; Radu, C.; Bhinder, B.; Li, Y.; Djaballah, H.; Kharas, M. G.
    Combinatorial Chemistry and High Throughput Screening (2014)

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  • A high-throughput scintillation proximity-based assay for human DNA ligase IV
    Journal Article

    Tseng, H. M.; Shum, D.; Bhinder, B.; Escobar, S.; Veomett, N. J.; Tomkinson, A. E.; Gin, D. Y.; Djaballah, H.; Scheinberg, D. A.
    Assay and Drug Development Technologies (2012)

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  • A high throughput scintillation proximity imaging assay for protein methyltransferases
    Journal Article

    Ibáñez, G.; Shum, D.; Blum, G.; Bhinder, B.; Radu, C.; Antczak, C.; Luo, M.; Djaballah, H.
    Combinatorial Chemistry and High Throughput Screening (2012)

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  • Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase
    Journal Article

    Antczak, C.; Shum, D.; Bassit, B.; Frattini, M. G.; Li, Y.; de Stanchina, E.; Scheinberg, D. A.; Djaballah, H.
    Bioorganic & Medicinal Chemistry Letters (2011)

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