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Brian Untch

  1. "Human Oncology and Pathogenesis Program"
Formats
  1. Journal Article (16)
  2. Meeting Abstract (6)
Groups
  1. Center for Pancreatic Cancer Research (22)
  2. Department of Medicine (22)
  3. GSK Faculty (22)
  4. Human Oncology and Pathogenesis Program (22)
  5. Surgery (22)
  6. Department of Pathology and Laboratory Medicine (19)

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People
  1. James Fagin (14)
  2. Ronald Ghossein (11)
  3. Michael Berger (9)
  4. Bin Xu (6)
  5. Ian Ganly (6)
  6. Robert Tuttle (6)

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Years
  1. 2025 (1)
  2. 2024 (3)
  3. 2022 (8)
  4. 2020 (2)
  5. 2019 (2)
  6. 2018 (3)

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Publications
  1. Journal of Clinical Oncology (4)
  2. Cancer Research (3)
  3. Thyroid (3)
  4. Clinical Cancer Research (2)
  5. Cancer Discovery (1)
  6. Genes Chromosomes and Cancer (1)

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Publishers
  1. American Association for Cancer Research (7)
  2. American Society of Clinical Oncology (5)
  3. Mary Ann Liebert, Inc (3)
  4. Nature Publishing Group (2)
  5. American Medical Association (1)
  6. Lippincott Williams & Wilkins (1)

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Results (22)

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  • RBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs
    Journal Article

    Krishnamoorthy, G. P.; Glover, A. R.; Untch, B. R.; Sigcha-Coello, N.; Xu, B.; Vukel, D.; Liu, Y.; Tiedje, V.; Pineda, J. M. B.; Berman, K.; more...
    Journal of Experimental Medicine (2025)

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  • Cooperative genomic lesions in HRAS-mutant cancers predict resistance to farnesyltransferase inhibitors
    Journal Article

    Nigam, A.; Krishnamoorthy, G. P.; Chatila, W. K.; Berman, K.; Saqcena, M.; Walch, H.; Venkatramani, M.; Ho, A. L.; Schultz, N.; Fagin, J. A.; more...
    Oncogene (2024)

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  • RAS-mutated cytologically indeterminate thyroid nodules: Prevalence of malignancy and behavior under active surveillance
    Journal Article

    Sfreddo, H. J.; Koh, E. S.; Zhao, K.; Swartzwelder, C. E.; Untch, B. R.; Marti, J. L.; Roman, B. R.; Dublin, J.; Wang, R. S.; Xia, R.; more...
    Thyroid (2024)

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  • Association of the genomic profile of medullary thyroid carcinoma with tumor characteristics and clinical outcomes in an international multicenter study
    Journal Article

    Xu, B.; Viswanathan, K.; Ahadi, M. S.; Ahmadi, S.; Alzumaili, B.; Bani, M. A.; Baudin, E.; Blake Behrman, D.; Capelletti, M.; Chau, N. G.; more...
    Thyroid (2024)

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  • RBM10 loss in thyroid cancer leads to aberrant splicing of cytoskeletal and extracellular matrix mRNAs and increased metastatic fitness
    Meeting Abstract

    Krishnamoorthy, G. P.; Glover, A.; Untch, B.; Saqcena, M.; Vukel, D.; Berman, K.; Abdel-Wahab, O.; Bradley, R. K.; Knauf, J. A.; Fagin, J. A.
    Cancer Research (2022)

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  • PTEN loss-of-function mutations prevalent in HRAS-mutant cancers results in resistance to targeted therapy
    Meeting Abstract

    Nigam, A.; Chatila, W. K.; Krishnamoorthy, G. P.; Ho, A. L.; Fagin, J. A.; Schultz, N. D.; Untch, B. R.
    Cancer Research (2022)

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  • Targeted sequencing of 2,138 bone and soft tissue sarcomas reveals commonly altered pathways, subtype-independent genetic clusters, and potential therapeutic targets
    Meeting Abstract

    Nacev, B. A.; Sanchez-Vega, F.; Smith, S.; Antonescu, C.; Rosenbaum, E.; Shi, H.; Tang, C.; Socci, N.; Rana, S.; Gularte-Merida, R.; more...
    Clinical Cancer Research (2022)

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  • Active surveillance of papillary thyroid cancer: Frequency and time course of the six most common tumor volume kinetic patterns
    Journal Article

    Tuttle, R. M.; Fagin, J.; Minkowitz, G.; Wong, R.; Roman, B.; Patel, S.; Untch, B.; Ganly, I.; Shaha, A.; Shah, J.; more...
    Thyroid (2022)

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  • Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets
    Journal Article

    Nacev, B. A.; Sanchez-Vega, F.; Smith, S. A.; Antonescu, C. R.; Rosenbaum, E.; Shi, H.; Tang, C.; Socci, N. D.; Rana, S.; Zehir, A.; more...
    Nature Communications (2022)

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  • FGFR2::TACC2 fusion as a novel KIT-independent mechanism of targeted therapy failure in a multidrug-resistant gastrointestinal stromal tumor
    Journal Article

    Dermawan, J. K.; Vanderbilt, C. M.; Chang, J. C.; Untch, B. R.; Singer, S.; Chi, P.; Tap, W. D.; Antonescu, C. R.
    Genes Chromosomes and Cancer (2022)

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