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Andrea D. Basso

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Meeting Abstract (19)
  2. Journal Article (12)
Groups
  1. Breast Medicine Service (31)
  2. Department of Medicine (31)
  3. GSK Faculty (31)
  4. Molecular Pharmacology and Chemistry Program Faculty (31)
  5. Sloan Kettering Institute Faculty (31)
  6. Solid Tumor Oncology Division (31)

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People
  1. Neal Rosen (31)
  2. David Solit (24)
  3. Pamela Munster (7)
  4. Howard Scher (6)
  5. Olivera Grbovic-Huezo (6)
  6. Ayana Sawai (5)

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Years
  1. 2006 (2)
  2. 2005 (3)
  3. 2004 (3)
  4. 2003 (8)
  5. 2002 (7)
  6. 2001 (6)

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Publications
  1. Cancer Research (8)
  2. Clinical Cancer Research (8)
  3. Proceedings of the American Association for Cancer Research Annual Meeting (6)
  4. Oncogene (2)
  5. Breast Cancer Research and Treatment (1)
  6. Chemistry and Biology (1)

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Publishers
  1. American Association for Cancer Research (22)
  2. Nature Publishing Group (3)
  3. Elsevier Inc. (2)
  4. American Society for Biochemistry and Molecular Biology (1)
  5. Bentham Science Publishers (1)
  6. National Academy of Sciences (1)

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Results (31)

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  • BRAF mutation predicts sensitivity to MEK inhibition
    Journal Article

    Solit, D. B.; Garraway, L. A.; Pratilas, C. A.; Sawai, A.; Getz, G.; Basso, A.; Ye, Q.; Lobo, J. M.; She, Y.; Osman, I.; more...
    Nature (2006)

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  • V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors
    Journal Article

    Grbovic, O. M.; Basso, A. D.; Sawai, A.; Ye, Q.; Friedlander, P.; Solit, D.; Rosen, N.
    Proceedings of the National Academy of Sciences of the United States of America (2006)

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  • Cyclin D expression and G1 progression are dependent on MEK MAP kinase activity in tumor cells with B-Raf mutation but not in breast cancer cells with wild type Ras and Raf
    Meeting Abstract

    Sawai, A.; Pratilas, C.; Basso, A.; Rosen, N.; Solit, D. B.
    Cancer Research (2005)

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  • V599E B-Raf as the next HSP90 client protein: A novel strategy for selective inhibition of mutated B-Raf
    Meeting Abstract

    Grbovic, O. M.; Basso, A.; Solit, D.; Rosen, N.
    Cancer Research (2005)

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  • Inhibitors of Hsp90 induce the degradation of HER2 and inhibit the growth of HER2-dependent breast tumors
    Meeting Abstract

    Solit, D. B.; Basso, A.; Smith-Jones, P.; Modi, S.; Norton, L.; Larson, S.; Neckers, L.; Scher, H.; Hudis, C.; Rosen, N.
    Breast Cancer Research and Treatment (2005)

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  • Cyclin D expression and G1 progression are dependent on MEK-MAP kinase activity in tumor cells with B-Raf mutation but not in breast cancer cells with wild type Ras and Raf
    Meeting Abstract

    Pratilas, C. A.; Grbovic, O.; Basso, A. D.; Sawai, A.; Chapman, P.; Rosen, N.; Solit, D. B.
    Cancer Research (2004)

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  • Activated, mutated B-raf protein kinase requires the HSP90 chaperone for folding and stability and is degraded in response to HSP90 inhibitors
    Meeting Abstract

    Grbovic, O. M.; Basso, A. D.; Friedlander, P.; Houghton, A.; Solit, D. B.; Rosen, N.
    Cancer Research (2004)

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  • Targeting wide-range oncogenic transformation via PU24FCI, a specific inhibitor of tumor Hsp90
    Journal Article

    Vilenchik, M.; Solit, D.; Basso, A.; Huezo, H.; Lucas, B.; He, H.; Rosen, N.; Spampinato, C.; Modrich, P.; Chiosis, G.
    Chemistry and Biology (2004)

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  • Response and resistance to gefitinib (ZD1839, Iressa) in HER overexpressing tumor cells is mediated through the PI3K/Akt pathway
    Meeting Abstract

    She, Q. B.; Solit, D.; Basso, A.; Rosen, N.; Moasser, M. M.
    Proceedings of the American Association for Cancer Research Annual Meeting (2003)

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  • Akt kinase is regulated by an Hsp90-Cdc37 complex
    Meeting Abstract

    Basso, A. D.; Rosen, N.
    Proceedings of the American Association for Cancer Research Annual Meeting (2003)

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