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Benjamin H Lok

  1. "Center for Molecular Imaging and Biotechnology"
Formats
  1. Journal Article (6)
  2. Meeting Abstract (3)
Groups
  1. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (9)
  2. Center for Molecular Imaging and Biotechnology (9)
  3. Department of Medicine (9)
  4. GSK Faculty (9)
  5. Solid Tumor Oncology Division (9)
  6. Thoracic Oncology (9)

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People
  1. Charles Rudin (9)
  2. John Poirier (9)
  3. Elisa De Stanchina (6)
  4. Brandon Carney (4)
  5. James Laird (4)
  6. Susanne Kossatz (4)

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Years
  1. 2019 (1)
  2. 2018 (3)
  3. 2017 (5)
Publications
  1. Clinical Cancer Research (2)
  2. Journal of Thoracic Oncology (2)
  3. Cancer Cell (1)
  4. International Journal of Radiation Oncology, Biology, Physics (1)
  5. Journal of Radiation Oncology (1)
  6. Nature Communications (1)

More Publications

Publishers
  1. Elsevier Inc. (3)
  2. American Association for Cancer Research (2)
  3. Nature Publishing Group (2)
  4. Cell Press (1)
  5. Springer (1)

Results (9)

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  • Positron-emission tomographic imaging of a fluorine 18-radiolabeled Poly(ADP-ribose) polymerase 1 inhibitor monitors the therapeutic efficacy of talazoparib in SCLC patient-derived xenografts
    Journal Article

    Laird, J.; Lok, B. H.; Carney, B.; Kossatz, S.; de Stanchina, E.; Reiner, T.; Poirier, J. T.; Rudin, C. M.
    Journal of Thoracic Oncology (2019)

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  • PARP inhibitor radiosensitization of small cell lung cancer differs by PARP trapping potency
    Meeting Abstract

    Lok, B.; Laird, J.; Ma, J.; De Stanchina, E.; Poirier, J.; Rudin, C.
    Journal of Thoracic Oncology (2018)

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  • Talazoparib is a potent radiosensitizer in small cell lung cancer cell lines and xenografts
    Journal Article

    Laird, J. H.; Lok, B. H.; Ma, J.; Bell, A.; de Stanchina, E.; Poirier, J. T.; Rudin, C. M.
    Clinical Cancer Research (2018)

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  • Target engagement imaging of PARP inhibitors in small-cell lung cancer
    Journal Article

    Carney, B.; Kossatz, S.; Lok, B. H.; Schneeberger, V.; Gangangari, K. K.; Pillarsetty, N. V. K.; Weber, W. A.; Rudin, C. M.; Poirier, J. T.; Reiner, T.
    Nature Communications (2018)

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  • [F18]PARPi PETas an in vivo biomarker of intratumoral parp inhibition in small cell lung cancer
    Meeting Abstract

    Lok, B.; Laird, J.; Carney, B.; Kossatz, S.; Reiner, T.; Poirier, J.; Rudin, C.
    Journal of Radiation Oncology (2017)

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  • [(18)F]PARPi PET as a marker of intratumoral talazoparib level in small cell lung cancer
    Meeting Abstract

    Laird, J. H.; Lok, B. H.; Carney, B.; Kossatz, S.; Ma, J.; Bell, A.; Shah, N.; Sadique, A.; De Stanchina, E.; Reiner, T.; more...
    International Journal of Radiation Oncology, Biology, Physics (2017)

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  • Unravelling the biology of SCLC: Implications for therapy
    Journal Article

    Sabari, J. K.; Lok, B. H.; Laird, J. H.; Poirier, J. T.; Rudin, C. M.
    Nature Reviews Clinical Oncology (2017)

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  • PARP Inhibitor activity correlates with SLFN11 expression and demonstrates synergy with temozolomide in small cell lung cancer
    Journal Article

    Lok, B. H.; Gardner, E. E.; Schneeberger, V. E.; Ni, A.; Desmeules, P.; Rekhtman, N.; De Stanchina, E.; Teicher, B. A.; Riaz, N.; Powell, S. N.; more...
    Clinical Cancer Research (2017)

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  • Chemosensitive relapse in small cell lung cancer proceeds through an EZH2-SLFN11 axis
    Journal Article

    Gardner, E. E.; Lok, B. H.; Schneeberger, V. E.; Desmeules, P.; Miles, L. A.; Arnold, P. K.; Ni, A.; Khodos, I.; de Stanchina, E.; Nguyen, T.; more...
    Cancer Cell (2017)

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