Synapse - Sadna Budhu

Results (86)

Isoform specific TGF-β inhibition in combination with radiation therapy as a novel immune therapeutic approach to cancer therapy

Meeting Abstract

Gupta, A.; Budhu, S.; Giese, R.; van Snick, J.; Uyttenhove, C.; Ritter, G.; Wolchok, J.; Merghoub, T.
Journal for ImmunoTherapy of Cancer (2017)

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Phosphatidylserine targeting antibody in combination with tumor radiation and immune checkpoint blockade promotes anti-tumor activity in mouse B16 melanoma

Meeting Abstract

Budhu, S.; Giese, R.; De Henau, O.; Zappasodi, R.; Campesato, L. F.; Gupta, A.; Barker, C.; Freimark, B.; Wolchok, J. D.; Merghoub, T.
Journal for ImmunoTherapy of Cancer (2017)

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Investigating the kynurenine pathway as a central effector mechanism of tumor immune-suppression and its potential as therapeutic target

Meeting Abstract

Campesato, L. F.; Budhu, S.; Zhang, X. M.; Manfredi, M. G.; McGovern, K.; Wolchok, J. D.; Merghoub, T.
Journal for ImmunoTherapy of Cancer (2017)

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Blockade of surface-bound TGF-ß on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment

Journal Article

Budhu, S.; Schaer, D. A.; Li, Y.; Toledo-Crow, R.; Panageas, K.; Yang, X.; Zhong, H.; Houghton, A. N.; Silverstein, S. C.; Merghoub, T.; more...
Science Signaling (2017)

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Combining radiotherapy and immunotherapy: Emerging preclinical observations of lymphocyte costimulatory and inhibitory receptor modulation

Book Section

Samstein, R. M.; Budhu, S.; Mergoub, T.; Barker, C. A.
In Tofilon, P. J.; Camphausen, K. (Eds.) Increasing the Therapeutic Ratio of Radiotherapy (2017)

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Opposing effects of CTLA-4 and PD-1 blockade on follicular helperlike T cells with immunosuppressive functions

Meeting Abstract

Zappasodi, R.; Budhu, S.; Hellmann, M. D.; Postow, M.; Senbabaoglu, Y.; Gasmi, B.; Zhong, H.; Li, Y.; Liu, C.; Hirschhorhn-Cymerman, D.; more...
Journal for ImmunoTherapy of Cancer (2016)

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Phosphatidylserine targeting antibody in combination with checkpoint blockade and tumor radiation therapy promotes anticancer activity in mouse melanoma

Meeting Abstract

Budhu, S.; De Henau, O.; Zappasodi, R.; Schlunegger, K.; Freimark, B.; Hutchins, J.; Barker, C. A.; Wolchok, J. D.; Merghoub, T.
Journal for ImmunoTherapy of Cancer (2016)

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Kinase regulation of human MHC class i molecule expression on cancer cells

Journal Article

Brea, E. J.; Oh, C. Y.; Manchado, E.; Budhu, S.; Gejman, R. S.; Mo, G.; Mondello, P.; Han, J. E.; Jarvis, C. A.; Ulmert, D.; more...
Cancer Immunology Research (2016)

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Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells

Journal Article

De Henau, O.; Rausch, M.; Winkler, D.; Campesato, L. F.; Liu, C.; Cymerman, D. H.; Budhu, S.; Ghosh, A.; Pink, M.; Tchaicha, J.; more...
Nature (2016)

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Treg inhibition by anti-GITR therapy evokes therapeutic antitumor responses selectively in the context of a pro-inflammatory tumor microenvironment

Meeting Abstract

Zappasodi, R.; Budhu, S.; Liu, C.; Draleau, K.; Schaer, D.; Zhong, H.; Yang, X.; Merghoub, T.; Wolchok, J. D.
Cancer Immunology Research (2016)

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