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Omar Ibrahim Abdel-Wahab

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Journal Article (23)
  2. Meeting Abstract (16)
Groups
  1. Center for Hematologic Malignancies (39)
  2. Department of Medicine (39)
  3. Executive Committee, Center for Hematologic Malignancies (39)
  4. GSK Faculty (39)
  5. Hematologic Malignancies, Division of (39)
  6. Molecular Pharmacology and Chemistry Program Faculty (39)

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People
  1. Neal Rosen (24)
  2. Ross Levine (14)
  3. Young Rock Chung (13)
  4. Eunhee Kim (11)
  5. Raajit Rampal (11)
  6. Benjamin Durham (10)

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Years
  1. 2024 (1)
  2. 2022 (3)
  3. 2021 (2)
  4. 2020 (1)
  5. 2019 (3)
  6. 2018 (2)

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Publications
  1. Blood (9)
  2. Cancer Discovery (6)
  3. Cancer Research (4)
  4. Nature (2)
  5. Nature Medicine (2)
  6. New England Journal of Medicine (2)

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Publishers
  1. American Association for Cancer Research (12)
  2. American Society of Hematology (9)
  3. Nature Publishing Group (6)
  4. Cell Press (2)
  5. Massachusetts Medical Society (2)
  6. American Association for the Advancement of Science (1)

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Results (39)

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  • Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia
    Journal Article

    Chung, S. S.; Kim, E.; Park, J. H.; Chung, Y. R.; Lito, P.; Teruya-Feldstein, J.; Hu, W.; Béguelin, W.; Monette, S.; Duy, C.; more...
    Science Translational Medicine (2014)

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  • Efficacy of intermittent combined RAF and MEK inhibition in a patient with concurrent BRAF- and NRAS-mutant malignancies
    Journal Article

    Abdel-Wahab, O.; Klimek, V. M.; Gaskell, A. A.; Viale, A.; Cheng, D.; Kim, E.; Rampal, R.; Bluth, M.; Harding, J. J.; Callahan, M. K.; more...
    Cancer Discovery (2014)

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  • Arginine methylation of RBM15 by PRMT1 controls alternative splicing of genes involved in megakaryocyte differentiation
    Meeting Abstract

    Zhao, X.; Zhang, L.; Wang, R.; Trans, N. T.; Su, H.; Abdel-Wahab, O.; Hrick, T.; Levine, R. L.; Deng, H.; Liu, Y.; more...
    Blood (2013)

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  • BRAFV600E mutations occur in the hematopoietic stem cell compartment in hairy cell leukemia
    Meeting Abstract

    Chung, S. S.; Park, J. H.; Kim, E.; Chung, Y. R.; Hu, W.; Lito, P.; Feldstein, J. T.; Rampal, R. K.; Telis, L.; Patel, M.; more...
    Blood (2013)

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  • Progression of RAS-mutant leukemia during RAF inhibitor treatment
    Journal Article

    Callahan, M. K.; Rampal, R.; Harding, J. J.; Klimek, V. M.; Chung, Y. R.; Merghoub, T.; Wolchok, J. D.; Solit, D. B.; Rosen, N.; Abdel-Wahab, O.; more...
    New England Journal of Medicine (2012)

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  • Heterodimeric JAK STAT activation as a mechanism of persistence to JAK2 inhibitor therapy
    Journal Article

    Koppikar, P.; Bhagwat, N.; Kilpivaara, O.; Manshouri, T.; Adli, M.; Hricik, T.; Liu, F.; Saunders, L. M.; Mullally, A.; Abdel-Wahab, O.; more...
    Nature (2012)

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  • Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy
    Meeting Abstract

    Bhagwat, N.; Koppikar, P.; Kilpivaara, O.; Manshouri, T.; Adli, M.; Mullally, A.; Abdel-Wahab, O.; Leung, L.; Weinstein, A.; Marubayashi, S.; more...
    Blood (2011)

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  • HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans
    Journal Article

    Marubayashi, S.; Koppikar, P.; Taldone, T.; Abdel-Wahab, O.; West, N.; Bhagwat, N.; Caldas-Lopes, E.; Ross, K. N.; Gonen, M.; Gozman, A.; more...
    Journal of Clinical Investigation (2010)

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  • Efficacy of the novel non-quinone based HSP-90 inhibitor PU-H71 in JAK2V617F and MPLW515L-induced murine models of myeloproliferative neoplasms
    Meeting Abstract

    Koppikar, P.; Marubayashi, S.; Taldone, T.; Abdel-Wahab, O.; West, N.; Gozman, A.; Ahn, J.; Rodina, A.; Bhagwat, N.; Hedvat, C. V.; more...
    Blood (2009)

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