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Omar Ibrahim Abdel-Wahab

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Journal Article (23)
  2. Meeting Abstract (16)
Groups
  1. Center for Hematologic Malignancies (39)
  2. Department of Medicine (39)
  3. Executive Committee, Center for Hematologic Malignancies (39)
  4. GSK Faculty (39)
  5. Hematologic Malignancies, Division of (39)
  6. Molecular Pharmacology and Chemistry Program Faculty (39)

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People
  1. Neal Rosen (24)
  2. Ross Levine (14)
  3. Young Rock Chung (13)
  4. Eunhee Kim (11)
  5. Raajit Rampal (11)
  6. Benjamin Durham (10)

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Years
  1. 2024 (1)
  2. 2022 (3)
  3. 2021 (2)
  4. 2020 (1)
  5. 2019 (3)
  6. 2018 (2)

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Publications
  1. Blood (9)
  2. Cancer Discovery (6)
  3. Cancer Research (4)
  4. Nature (2)
  5. Nature Medicine (2)
  6. New England Journal of Medicine (2)

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Publishers
  1. American Association for Cancer Research (12)
  2. American Society of Hematology (9)
  3. Nature Publishing Group (6)
  4. Cell Press (2)
  5. Massachusetts Medical Society (2)
  6. American Association for the Advancement of Science (1)

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Results (39)

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  • BRAF mutants evade ERK-dependent feedback by different mechanisms that determine their sensitivity to pharmacologic inhibition
    Journal Article

    Yao, Z.; Torres, N. M.; Tao, A.; Gao, Y.; Luo, L.; Li, Q.; de Stanchina, E.; Abdel-Wahab, O.; Solit, D. B.; Poulikakos, P. I.; more...
    Cancer Cell (2015)

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  • Diverse kinase mutations and fusions drive non-Langerhans cell histiocytoses
    Meeting Abstract

    Durham, B.; Diamond, E.; Yao, Z.; Ma, J.; Choi, J.; Kim, E.; Lee, S.; Gao, Y.; Micol, J. B.; Campbell, P.; more...
    Pediatric Blood and Cancer (2015)

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  • Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders
    Journal Article

    Hyman, D. M.; Diamond, E. L.; Vibat, C. R. T.; Hassaine, L.; Poole, J. C.; Patel, M.; Holley, V. R.; Cabrilo, G.; Lu, T. T.; Arcila, M. E.; more...
    Cancer Discovery (2015)

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  • Oncogenic RAF mutants that signal as functional dimers are resistant to current RAF inhibitors but sensitive to a novel inhibitor of RAF dimer kinase activity
    Meeting Abstract

    Yao, Z.; Torres, N. M.; Wei, M.; Hanrahan, A.; Abdel-Wahab, O.; Solit, D.; Luo, L.; Poulikakos, P.; Rosen, N.
    Molecular Cancer Research (2014)

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  • Oncogenic RAF mutants that signal as functional dimers are resistant to current RAF inhibitors but sensitive to a novel inhibitor of RAF dimer kinase activity
    Meeting Abstract

    Yao, Z.; Torres, M.; Wei, M.; Hanrahan, A.; Abdel-Wahab, O.; Solit, D.; Luo, L. S.; Poulikakos, P.; Rosen, N.
    Cancer Research (2014)

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  • Context specific effects of the BRAFV600E mutation on hematopoiesis identifies novel models of BRAF mutant hematopoietic disorders
    Meeting Abstract

    Kim, E.; Chung, S. S.; Park, J. H.; Chung, Y. R.; Lito, P.; Feldstein, J.; Hu, W. H.; Beguilin, W.; Monette, S.; Duy, C.; more...
    Cancer Research (2014)

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  • Vemurafenib has potent antitumor activity in patients with relapsed/refractory BRAF mutant hairy cell leukemia
    Meeting Abstract

    Park, J. H.; Chung, S. S.; Chung, Y. R.; Won, H.; Kim, E.; Saven, A.; Wadleigh, M.; Stone, R. M.; Barrientos, J. C.; Rai, K. R.; more...
    Blood (2014)

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  • The Warburg effect confers adverse outcome in chronic lymphocytic leukemia
    Meeting Abstract

    Gardner, J. R.; Devlin, S. M.; Knapp, K.; Bauli, F.; Patel, M.; Lamanna, N.; Frattini, M. G.; Brentjens, R.; Maslak, P.; Jurcic, J. G.; more...
    Clinical Lymphoma, Myeloma and Leukemia (2014)

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  • Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms
    Journal Article

    Rampal, R.; Ahn, J.; Abdel-Wahab, O.; Nahas, M.; Wang, K.; Lipson, D.; Otto, G. A.; Yelensky, R.; Hricik, T.; McKenney, A. S.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2014)

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  • Brafv600e mutations in hematopoietic stem cells of hairy cell leukemia patients suggests a stem cell origin
    Meeting Abstract

    Chung, S. S.; Kim, E.; Park, J. H.; Chung, Y. R.; Feldstein, J.; Hu, W.; Rampal, R.; Patel, M.; Kim, M. K.; Huberman, K.; more...
    Haematologica (2014)

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