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Peter Besmer

  1. "Surgery"
Formats
  1. Journal Article (23)
  2. Meeting Abstract (8)
Groups
  1. Department of Pathology and Laboratory Medicine (31)
  2. Developmental Biology Program Faculty (31)
  3. GSK Faculty (31)
  4. Sloan Kettering Institute Faculty (31)
  5. Surgery (31)
  6. Tow Center for Developmental Oncology (TCDO) (31)

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People
  1. Cristina Antonescu (31)
  2. Ronald DeMatteo (29)
  3. Robert Maki (16)
  4. Tianhua Guo (11)
  5. Narasimhan Agaram (9)
  6. Ferdinando Rossi (8)

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Years
  1. 2020 (1)
  2. 2017 (3)
  3. 2015 (1)
  4. 2014 (1)
  5. 2013 (1)
  6. 2012 (2)

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Publications
  1. Clinical Cancer Research (10)
  2. Laboratory Investigation (4)
  3. Modern Pathology (4)
  4. Genes Chromosomes and Cancer (2)
  5. BMC Cancer (1)
  6. Cancer (1)

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Publishers
  1. American Association for Cancer Research (12)
  2. Nature Publishing Group (6)
  3. Nature Research (4)
  4. Wiley Periodicals, Inc (2)
  5. Biomed Central Ltd (1)
  6. Informa Healthcare (1)

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Results (31)

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  • The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor
    Journal Article

    Zhang, J. Q.; Bosbach, B.; Loo, J. K.; Vitiello, G. A.; Zeng, S.; Seifert, A. M.; Medina, B. D.; Param, N. J.; Maltbaek, J. H.; Rossi, F.; more...
    Oncogene (2020)

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  • Direct engagement of the PI3K pathway by mutant KIT dominates oncogenic signaling in gastrointestinal stromal tumor
    Journal Article

    Bosbach, B.; Rossi, F.; Yozgat, Y.; Loo, J.; Zhang, J. Q.; Berrozpe, G.; Warpinski, K.; Ehlers, I.; Veach, D.; Kwok, A.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2017)

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  • Wnt/β-catenin signaling contributes to tumor malignancy and is targetable in gastrointestinal stromal tumor
    Journal Article

    Zeng, S.; Seifert, A. M.; Zhang, J. Q.; Cavnar, M. J.; Kim, T. S.; Balachandran, V. P.; Santamaria-Barria, J. A.; Cohen, N. A.; Beckman, M. J.; Medina, B. D.; more...
    Molecular Cancer Therapeutics (2017)

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  • PD-1/PD-L1 blockade enhances T-cell activity and antitumor efficacy of imatinib in gastrointestinal stromal tumors
    Journal Article

    Seifert, A. M.; Zeng, S.; Zhang, J. Q.; Kim, T. S.; Cohen, N. A.; Beckman, M. J.; Medina, B. D.; Maltbaek, J. H.; Loo, J. K.; Crawley, M. H.; more...
    Clinical Cancer Research (2017)

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  • Pharmacological inhibition of KIT activates MET signaling in gastrointestinal stromal tumors
    Journal Article

    Cohen, N. A.; Zeng, S.; Seifert, A. M.; Kim, T. S.; Sorenson, E. C.; Greer, J. B.; Beckman, M. J.; Santamaria-Barria, J. A.; Crawley, M. H.; Green, B. L.; more...
    Cancer Research (2015)

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  • Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor
    Journal Article

    Kim, T. S.; Cavnar, M. J.; Cohen, N. A.; Sorenson, E. C.; Greer, J. B.; Seifert, A. M.; Crawley, M. H.; Green, B. L.; Popow, R.; Pillarsetty, N.; more...
    Clinical Cancer Research (2014)

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  • KIT oncogene inhibition drives intratumoral macrophage M2 polarization
    Journal Article

    Cavnar, M. J.; Zeng, S.; Kim, T. S.; Sorenson, E. C.; Ocuin, L. M.; Balachandran, V. P.; Seifert, A. M.; Greer, J. B.; Popow, R.; Crawley, M. H.; more...
    Journal of Experimental Medicine (2013)

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  • SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors
    Journal Article

    Italiano, A.; Chen, C. L.; Sung, Y. S.; Singer, S.; DeMatteo, R. P.; LaQuaglia, M. P.; Besmer, P.; Socci, N.; Antonescu, C. R.
    BMC Cancer (2012)

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  • CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers
    Journal Article

    Chen, J.; Guo, T.; Zhang, L.; Qin, L. X.; Singer, S.; Maki, R. G.; Taguchi, T.; DeMatteo, R.; Besmer, P.; Antonescu, C. R.
    Genes Chromosomes and Cancer (2012)

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  • Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
    Journal Article

    Balachandran, V. P.; Cavnar, M. J.; Zeng, S.; Bamboat, Z. M.; Ocuin, L. M.; Obaid, H.; Sorenson, E. C.; Popow, R.; Ariyan, C.; Rossi, F.; more...
    Nature Medicine (2011)

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