Synapse - Bayard Clarkson

Results (220)

A cell-based screen for resistance of Bcr-Abl-positive leukemia identifies the mutation pattern for PD166326, an alternative Abl kinase inhibitor

Journal Article

Von Bubnoff, N.; Veach, D. R.; Van Der Kuip, H.; Aulitzky, W. E.; Sanger, J.; Seipel, P.; Bornmann, W. G.; Peschel, C.; Clarkson, B.; Duyster, J.
Blood (2005)

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Synthesis and in vitro examination of [(124)I]-, [(125)I]- and [(131)I]-2-(4-iodophenylamino) pyrido[2,3-d]pyrimidin-7-one radiolabeled Abl kinase inhibitors

Journal Article

Veach, D. R.; Namavari, M.; Beresten, T.; Balatoni, J.; Minchenko, M.; Djaballah, H.; Finn, R. D.; Clarkson, B.; Gelovani, J. G.; Bornmann, W. G.; more...
Nuclear Medicine and Biology (2005)

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A cell-based screening method for resistance of Bcr-Abl positive leukemia identifies the mutation pattern for an alternative abl kinase inhibitor

Meeting Abstract

Von Bubnoff, N.; Veach, D. R.; Van Der Kuip, H.; Aulitzky, W. E.; Saenger, J.; Seipel, P.; Bornmann, W. G.; Peschel, C.; Clarkson, B.; Duyster, J.
Blood (2004)

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Efficacy of dual-specific Bcr-Abl and Src-family kinase inhibitors in cells sensitive and resistant to imatinib mesylate

Journal Article

Tipping, A. J.; Baluch, S.; Barnes, D. J.; Veach, D. R.; Clarkson, B.; Bornmann, W. G.; Mahon, F. X.; Goldman, J. M.; Melo, J. V.
Leukemia (2004)

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Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation

Journal Article

Deng, X.; Hofmann, E. R.; Villanueva, A.; Hobert, O.; Capodieci, P.; Veach, D. R.; Yin, X.; Campodonico, L.; Glekas, A.; Cordon-Cardo, C.; more...
Nature Genetics (2004)

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Synthesis, in silico, in vitro and in vivo characterization of pyrido(2,3-d)pyrimidine tyrosine kinase inhibitors

Meeting Abstract

Veach, D. R.; Lambek, C.; Liu, C. Y.; Beresten, T.; Wisniewski, D.; Li, W.; Wolff, N. C.; Ilaria, R. L. Jr; Gelovani, J.; Bornmann, W. G.; more...
Proceedings of the American Association for Cancer Research Annual Meeting (2003)

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PD166326, a novel tyrosine kinase inhibitor, has greater anti-leukemic activity than imatinib in a murine model of chronic myelogenous leukemia

Meeting Abstract

Wolff, N. C.; Veach, D. R.; Tong, W. P.; Bornmann, W. G.; Clarkson, B.; Ilaria, R. L.
Blood (2003)

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Pyrido-pyrimidine kinase inhibitors suppress wild-type and mutant Bcr-Abl

Meeting Abstract

Von Bubnoff, N.; Veach, D. R.; Miller, W. T.; Li, W. Q.; Saenger, J.; Peschel, C.; Bornmann, W. G.; Clarkson, B.; Duyster, J.
Blood (2003)

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Synthesis, in vitro, and in vivo characterization of pyrido[2,3-D]pyrimidine tyrosine kinase inhibitors

Meeting Abstract

Veach, D. R.; Lambek, C.; Liu, C. Y.; Duyster, J.; Beresten, T.; Li, W. Q.; Wolff, N. C.; Ilaria, R. L.; Gelovani, J.; Miller, W. T.; more...
Abstracts of Papers of the American Chemical Society (2003)

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Efficacy of dual-specific Bcr-Abl and Src-family kinase inhibitors in cells sensitive and resistant to imatinib mesylate

Meeting Abstract

Tipping, A. J.; Baluch, S.; Mahon, F. X.; Veach, D. R.; Bornmann, W. G.; Clarkson, B. D; Goldman, J. M.; Melo, J. V.
Blood (2003)

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