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Howard Scher

  1. "Executive Committee, Center for Hematologic Malignancies"
Formats
  1. Journal Article (30)
  2. Meeting Abstract (19)
  3. Guidelines (1)
Groups
  1. Center for Hematologic Malignancies (50)
  2. Department of Medicine (50)
  3. Executive Committee, Center for Hematologic Malignancies (50)
  4. GSK Faculty (50)
  5. Genitourinary Oncology Service (50)
  6. Hematologic Malignancies, Division of (50)

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People
  1. Charles Sawyers (43)
  2. Nikolaus Schultz (17)
  3. Yu Chen (17)
  4. Michael Morris (15)
  5. Wassim Abida (15)
  6. Anuradha Gopalan (14)

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Years
  1. 2024 (2)
  2. 2023 (1)
  3. 2022 (2)
  4. 2020 (4)
  5. 2019 (4)
  6. 2018 (6)

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Publications
  1. Journal of Clinical Oncology (11)
  2. Cancer Research (8)
  3. Cancer Cell (3)
  4. Blood (2)
  5. Cell (2)
  6. JAMA Oncology (2)

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Publishers
  1. American Society of Clinical Oncology (13)
  2. American Association for Cancer Research (9)
  3. Nature Publishing Group (6)
  4. Cell Press (5)
  5. American Medical Association (3)
  6. American Society for Clinical Investigation (2)

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Results (50)

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  • The immunomodulatory protein Dickkopf-1 (DKK1) defines a non-neuroendocrine subtype of metastatic castration-resistant prostate cancer (mCRPC) with low AR and low PSA expression
    Meeting Abstract

    Wise, D.; Armenia, J.; Chen, Y.; Nelson, P.; Schultz, N.; Sawyers, C. L.; Scher, H. I.
    Journal of Clinical Oncology (2017)

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  • Mutation detection in patients with advanced cancer by universal sequencing of cancer-related genes in tumor and normal DNA vs guideline-based germline testing
    Journal Article

    Mandelker, D.; Zhang, L.; Kemel, Y.; Stadler, Z. K.; Joseph, V.; Zehir, A.; Pradhan, N.; Arnold, A.; Walsh, M. F.; Li, Y.; more...
    JAMA - Journal of the American Medical Association (2017)

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  • ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis
    Journal Article

    Bose, R.; Karthaus, W. R.; Armenia, J.; Abida, W.; Iaquinta, P. J.; Zhang, Z.; Wongvipat, J.; Wasmuth, E. V.; Shah, N.; Sullivan, P. S.; more...
    Nature (2017)

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  • Inherited DNA-repair gene mutations in men with metastatic prostate cancer
    Journal Article

    Pritchard, C. C.; Mateo, J.; Walsh, M. F.; De Sarkar, N.; Abida, W.; Beltran, H.; Garofalo, A.; Gulati, R.; Carreira, S.; Eeles, R.; more...
    New England Journal of Medicine (2016)

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  • Integrative clinical genomics of advanced prostate cancer
    Journal Article

    Robinson, D.; Van Allen, E. M.; Wu, Y. M.; Schultz, N.; Lonigro, R. J.; Mosquera, J. M.; Montgomery, B.; Taplin, M. E.; Pritchard, C. C.; Attard, G.; more...
    Cell (2015)

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  • Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ
    Journal Article

    Schwartz, S.; Wongvipat, J.; Trigwell, C. B.; Hancox, U.; Carver, B. S.; Rodrik-Outmezguine, V. ; Will, M.; Yellen, P.; de Stanchina, E.; Baselga, J.; more...
    Cancer Cell (2015)

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  • Development of novel metastatic prostate cancer cell lines by 'organoid' in vitro culture technology
    Meeting Abstract

    Vela, I.; Gao, D.; Gopalan, A.; Sboner, A.; Undvall, E.; Wanjala, J.; Iaquinta, P.; Wongvipat, J.; Dowling, C.; Karthaus, W.; more...
    BJU International (2015)

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  • Targeting reciprocal feedback inhibition in the clinic: ARN509 and PI3K pathway inhibition in patients with metastatic castration-resistant prostate cancer (mCRPC)
    Meeting Abstract

    Rathkopf, D. E.; Carver, B. S.; Chen, Y.; Morris, M. J.; Danila, D. C.; Slovin, S. F.; Autio, K. A.; DeNunzio, M.; Sawyers, C. L.; Scher, H. I.
    Journal of Clinical Oncology (2014)

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  • The antitumor effects of PI3K beta inhibitors in PTEN negative prostate cancer are enhanced by inhibition of reactivated PI3K alpha signaling
    Meeting Abstract

    Schwartz, S.; Carver, B. S.; Wongvipat, J.; Rodrik-Outmezguine, V. ; Destanchina, E.; Trigwell, C.; Barry, S.; Baselga, J.; Chandarlapaty, S.; Scher, H. I.; more...
    Cancer Research (2014)

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  • Organoid cultures derived from patients with advanced prostate cancer
    Journal Article

    Gao, D.; Vela, I.; Sboner, A.; Iaquinta, P. J.; Karthaus, W. R.; Gopalan, A.; Dowling, C.; Wanjala, J. N.; Undvall, E. A.; Arora, V. K.; more...
    Cell (2014)

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