Synapse - Efsevia Vakiani

Results (33)

Genetic predictors of response to systemic therapy in esophagogastric cancer

Journal Article

Janjigian, Y. Y.; Sanchez-Vega, F.; Jonsson, P.; Chatila, W. K.; Hechtman, J. F.; Ku, G. Y.; Riches, J. C.; Tuvy, Y.; Kundra, R.; Bouvier, N.; more...
Cancer Discovery (2018)

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Clinical sequencing defines the genomic landscape of metastatic colorectal cancer

Journal Article

Yaeger, R.; Chatila, W. K.; Lipsyc, M. D.; Hechtman, J. F.; Cercek, A.; Sanchez-Vega, F.; Jayakumaran, G.; Middha, S.; Zehir, A.; Donoghue, M. T. A.; more...
Cancer Cell (2018)

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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

Journal Article

Zehir, A.; Benayed, R.; Shah, R. H.; Syed, A.; Middha, S.; Kim, H. R.; Srinivasan, P.; Gao, J.; Chakravarty, D.; Devlin, S. M.; more...
Nature Medicine (2017)

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Morphological characterization of colorectal cancers in the Cancer Genome Atlas reveals distinct morphology-molecular associations: Clinical and biological implications

Journal Article

Shia, J.; Schultz, N.; Kuk, D.; Vakiani, E.; Middha, S.; Segal, N. H.; Hechtman, J. F.; Berger, M. F.; Stadler, Z. K.; Weiser, M. R.; more...
Modern Pathology (2017)

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Emergence of RTK/RAS/PI3K pathway alterations in trastuzumab-refractory HER2-positive esophagogastric (EG) tumors

Meeting Abstract

Janjigian, Y. Y.; Sanchez-Vega, F.; Tuvy, Y.; Bouvier, N.; Riches, J. C.; Margolis, M.; Millang, B. M.; Scott, S. N.; Kundra, R.; Castel, P.; more...
Journal of Clinical Oncology (2016)

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Clinical next generation sequencing (NGS) of esophagogastric (EG) adenocarcinomas identifies distinct molecular signatures of response to HER2 inhibition, first-line 5FU/platinum and PD1/CTLA4 blockade

Meeting Abstract

Janjigian, Y. Y.; Sanchez-Vega, F.; Jonsson, P.; Tuvy, Y.; Bouvier, N.; Riches, J.; Kundra, R.; Ku, G.; Hechtman, J. F.; Kelsen, D.; more...
Annals of Oncology (2016)

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Recurrent, truncating Sox9 mutations are associated with sox9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma

Journal Article

Javier, B. M.; Yaeger, R.; Wang, L.; Sanchez-Vega, F.; Zehir, A.; Middha, S.; Sadowska, J.; Vakiani, E.; Shia, J.; Klimstra, D.; more...
Oncotarget (2016)

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Comprehensive morphological assessment of colorectal cancers characterized by The Cancer Genome Atlas (TCGA) identifies specific morphology-molecular alteration associations

Meeting Abstract

Shia, J. R.; Kuk, D.; Schultz, N.; Berger, M.; Middha, S.; Vakiani, E.; Hechtman, J.; Stadler, Z.; Weiser, M.; Gonen, M.; more...
Modern Pathology (2016)

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Comprehensive morphological assessment of colorectal cancers characterized by The Cancer Genome Atlas (TCGA) identifies specific morphology-molecular alteration associations

Meeting Abstract

Shia, J. R.; Kuk, D.; Schultz, N.; Berger, M.; Middha, S.; Vakiani, E.; Hechtman, J.; Stadler, Z.; Weiser, M.; Gonen, M.; more...
Laboratory Investigation (2016)

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Genomic profiling of esophagogastric (EG) tumors in clinical practice

Meeting Abstract

Riches, J. C.; Schultz, N.; Ku, G. Y.; Imtiaz, T.; Kelsen, D. P.; Ilson, D. H.; Solit, D. B.; Berger, M. F.; Ladanyi, M.; Arcila, M. E.; more...
Journal of Clinical Oncology (2015)

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