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Hong Xu

Formats
  1. Journal Article (29)
  2. Meeting Abstract (25)
Groups
  1. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (54)
  2. Center for Molecular Imaging and Biotechnology (CMIB) (54)
  3. GSK Faculty (54)
  4. Neuroblastoma Service (54)
  5. Pediatrics, Department of (54)
  6. Sloan Kettering Institute Postdocs (54)

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People
  1. Nai-Kong Cheung (54)
  2. Hong-Fen Guo (37)
  3. Steven Larson (26)
  4. Sarah Cheal (20)
  5. Darren Veach (18)
  6. Blesida Punzalan (14)

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Years
  1. 2025 (2)
  2. 2024 (5)
  3. 2023 (2)
  4. 2022 (5)
  5. 2021 (6)
  6. 2020 (7)

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Publications
  1. Journal of Nuclear Medicine (14)
  2. Cancer Research (6)
  3. Cancer Immunology Research (3)
  4. Molecular Cancer Therapeutics (3)
  5. Nuclear Medicine and Biology (3)
  6. OncoImmunology (3)

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Publishers
  1. Society of Nuclear Medicine (14)
  2. American Association for Cancer Research (12)
  3. Biomed Central Ltd (3)
  4. Elsevier Science Inc. (3)
  5. Ivyspring International Publisher (3)
  6. Landes Bioscience (3)

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Results (54)

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  • Successful engineering of a highly potent single-chain variable-fragment (scFv) bispecific antibody to target disialoganglioside (GD2) positive tumors
    Journal Article

    Cheng, M.; Santich, B. H.; Xu, H.; Ahmed, M.; Huse, M.; Cheung, N. K. V.
    OncoImmunology (2016)

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  • Theranostic pretargeted radioimmunotherapy of colorectal cancer xenografts in mice using picomolar affinity (86)Y- or (177)Lu-DOTA-Bn binding scFv C825/GPA33 IgG bispecific immunoconjugates
    Journal Article

    Cheal, S. M.; Xu, H.; Lee, S. G.; Guo, H. F.; Punzalan, B.; Chalasani, S.; Fung, E.; Jungbluth, A.; Zanzonico, P.; Carrasquillo, J.; more...
    European Journal of Nuclear Medicine and Molecular Imaging (2016)

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  • Retargeting T cells to GD2 pentasaccharide on human tumors using bispecific humanized antibody
    Journal Article

    Xu, H.; Cheng, M.; Guo, H.; Chen, Y.; Huse, M.; Cheung, N. K. V.
    Cancer Immunology Research (2015)

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  • Structural design of disialoganglioside GD2 and CD3-bispecific antibodies to redirect T cells for tumor therapy
    Journal Article

    Cheng, M.; Ahmed, M.; Xu, H.; Cheung, N. K. V.
    International Journal of Cancer (2015)

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  • Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis
    Journal Article

    Cheung, I. Y.; Farazi, T. A.; Ostrovnaya, I.; Xu, H.; Tran, H.; Mihailovic, A.; Tuschl, T.; Cheung, N. K. V.
    Genes Chromosomes and Cancer (2014)

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  • Preclinical evaluation of multistep targeting of diasialoganglioside GD2 using an IgG-scFv bispecific antibody with high affinity for GD2 and DOTA metal complex
    Journal Article

    Cheal, S. M.; Xu, H.; Guo, H. F. ; Zanzonico, P. B.; Larson, S. M.; Cheung, N. K.
    Molecular Cancer Therapeutics (2014)

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  • Checkpoint kinase inhibitor synergizes with DNA-damaging agents in G 1 checkpoint-defective neuroblastoma
    Journal Article

    Xu, H.; Cheung, I. Y.; Wei, X. X.; Tran, H.; Gao, X.; Cheung, N. K. V.
    International Journal of Cancer (2011)

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  • Exploiting the defective p53/MDM2/p14(ARF) pathway in neuroblastoma by targeting checkpoint kinase Chk1 with AZD7762
    Meeting Abstract

    Xu, H.; Wei, X.; Cheung, I. Y.; Cheung, N. K. V.
    Cancer Research (2010)

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  • Compartmental intrathecal radioimmunotherapy: Results for treatment for metastatic CNS neuroblastoma
    Journal Article

    Kramer, K.; Kushner, B. H.; Modak, S.; Pandit-Taskar, N.; Smith-Jones, P.; Zanzonico, P.; Humm, J. L.; Xu, H.; Wolden, S. L.; Souweidane, M. M.; more...
    Journal of Neuro-Oncology (2010)

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  • Radically changing the natural history of metastatic central nervous system cancer: A pilot study incorporating compartmental intrathecal radioimmunotherapy
    Meeting Abstract

    Cheung, N. K.; Kramer, K.; Kushner, B. H.; Modak, S.; Pandit-Taskar, N.; Smith-Jones, P.; Zanzonico, P.; Humm, J. L.; Xu, H.; Wolden, S. L.; more...
    Journal of Pediatric Hematology/Oncology (2009)

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