Synapse - Hong Xu

Results (54)

Cancer immunotherapy via targeted TGF-β signalling blockade in T(H) cells

Journal Article

Li, S.; Liu, M.; Do, M. H.; Chou, C.; Stamatiades, E. G.; Nixon, B. G.; Shi, W.; Zhang, X.; Li, P.; Gao, S.; more...
Nature (2020)

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Multicycle pretargeted radioimmunotherapy using 177(Lu) for intraperitoneal GPA33-expressing colorectal xenografts

Meeting Abstract

Chandler, C.; Cheal, S.; Nash, G.; Cercek, A.; Punzalan, B.; Veach, D.; Xu, H.; Guo, H. F.; Larson, S.; Cheung, N. K.
Journal of Nuclear Medicine (2020)

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Pretargeted radioimmunotherapy using 225(Ac) for intraperitoneal GPA33-expressing colorectal xenografts

Meeting Abstract

Chandler, C.; Cheal, S.; Nash, G.; Cercek, A.; McDevitt, M.; Xu, H.; Guo, H. F.; Cheung, N. K.; Larson, S.
Journal of Nuclear Medicine (2020)

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Pretargeted alpha radioimmunotherapy (DOTA-PRIT) for HER2-expressing human gastric cancer: A theranostic approach using 111(In)/225(Ac)-radiohapten

Meeting Abstract

Cheal, S.; McDevitt, M.; Burnes Vargas, D.; Veach, D.; Punzalan, B.; Xu, H.; Guo, H. F.; Ouerfelli, O.; Cheung, N. K.; Larson, S.
Journal of Nuclear Medicine (2020)

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(225)Ac-alpha pretargeted radioimmunotherapy (DOTA-PRIT) of human colorectal cancer: Achieving 100% complete responses with single-cycle targeting of 2 distinct antigens, HER2 and GPA33

Meeting Abstract

Cheal, S.; McDevitt, M.; Burnes Vargas, D.; Veach, D.; Punzalan, B.; Xu, H.; Guo, H. F.; Ouerfelli, O.; Larson, S.; Cheung, N. K.
Journal of Nuclear Medicine (2020)

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Alpha radioimmunotherapy using (225)Ac-proteus-DOTA for solid tumors – Safety at curative doses

Journal Article

Cheal, S. M.; McDevitt, M. R.; Santich, B. H.; Patel, M.; Yang, G.; Fung, E. K.; Veach, D. R.; Bell, M.; Ahad, A.; Burnes Vargas, D.; more...
Theranostics (2020)

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An N-acetylgalactosamino dendron-clearing agent for high-therapeutic-index DOTA-hapten pretargeted radioimmunotherapy

Journal Article

Cheal, S. M.; Patel, M.; Yang, G.; Veach, D.; Xu, H.; Guo, H. F.; Zanzonico, P. B.; Axworthy, D. B.; Cheung, N. K. V.; Ouerfelli, O.; more...
Bioconjugate Chemistry (2020)

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PD-L1 checkpoint blockade augments anti-tumor immune response of GD2 or HER2-BsAb ex vivo armed T-cells (EVAT) therapy in osteosarcoma

Meeting Abstract

Park, J. A.; Guo, H. F.; Xu, H.; Cheung, N. K. V.
Blood (2019)

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Silencing Fc domains in T cell-engaging bispecific antibodies improves t-cell trafficking and antitumor potency

Journal Article

Wang, L.; Hoseini, S. S.; Xu, H.; Ponomarev, V.; Cheung, N. K.
Cancer Immunology Research (2019)

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Tetravalent bispecific antibodies specific for HER2 and disialoganglioside GD2 to engage polyclonal T cells for osteosarcoma therapy

Meeting Abstract

Park, J. A.; Xu, H.; Cheung, I.; Cheung, N. K. V.
Cancer Research (2018)

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