Synapse - Yueming Li

Results (132)

High-throughput identification of inhibitors of human mitochondrial peptide deformylase

Journal Article

Antczak, C.; Shum, D.; Escobar, S.; Bassit, B.; Kim, E.; Seshan, V. E.; Wu, N.; Yang, G.; Ouerfelli, O.; Li, Y. M.; more...
Journal of Biomolecular Screening (2007)

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Disrupting the notch pathway with gamma-secretase inhibitors suppresses growth and induces apoptosis of sarcoma cell lines with constitutively active ras and notch signaling pathways

Meeting Abstract

Meng, R. D.; Shelton, C. C.; Li, Y.; Schwartz, G. K.
Cancer Research (2006)

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Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

Meeting Abstract

Fan, X.; Matsui, W.; Khaki, L.; Stearns, D.; Chun, J.; Li, Y. M.; Eberhart, C. G.
Neuro-Oncology (2006)

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c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

Journal Article

Weng, A. P.; Millholland, J. M.; Yashiro-Ohtani, Y.; Arcangeli, M. L.; Lau, A.; Wai, C.; Del Bianco, C.; Rodriguez, C. G.; Sai, H.; Tobias, J.; more...
Genes and Development (2006)

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Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

Journal Article

Fan, X.; Matsui, W.; Khaki, L.; Stearns, D.; Chun, J.; Li, Y. M.; Eberhart, C. G.
Cancer Research (2006)

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Deletion of presenilin 1 hydrophilic loop sequence leads to impaired γ-secretase activity and exacerbated amyloid pathology

Journal Article

Deng, Y.; Tarassishin, L.; Kallhoff, V.; Peethumnongsin, E.; Wu, L.; Li, Y. M.; Zheng, H.
The Journal of Neuroscience (2006)

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Total synthesis of (±)-jiadifenin and studies directed to understanding its SAR: Probing mechanistic and stereochemical issues in palladium-mediated allylation of enolate-like structures

Journal Article

Carcache, D. A.; Cho, Y. S.; Hua, Z.; Tian, Y.; Li, Y. M.; Danishefsky, S. J.
Journal of the American Chemical Society (2006)

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Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production

Journal Article

Waters, S. P.; Tian, Y.; Li, Y. M.; Danishefsky, S. J.
Journal of the American Chemical Society (2005)

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Total synthesis as a resource in drug discovery: The first in vivo evaluation of panaxytriol and its derivatives

Journal Article

Yun, H.; Chou, T. C.; Dong, H.; Tian, Y.; Li, Y. M.; Danishefsky, S. J.
Journal of Organic Chemistry (2005)

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Novel mutations introduced at the β-site of amyloid β protein precursor enhance the production of amyloid β peptide by BACE1 in vitro and in cells

Journal Article

Shi, X. P.; Tugusheva, K.; Bruce, J. E.; Lucka, A.; Chen-Dodson, E.; Hu, B.; Wu, G. X.; Price, E.; Register, R. B.; Lineberger, J.; more...
Journal of Alzheimer's Disease (2005)

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