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Yueming Li

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Journal Article (96)
  2. Meeting Abstract (22)
  3. Review (9)
  4. Research Letter (3)
  5. Book Section (1)
  6. Editorial (1)
Groups
  1. GSK Faculty (132)
  2. Molecular Pharmacology and Chemistry Program Faculty (132)
  3. Population Sciences Research Program (132)
  4. Sloan Kettering Institute Faculty (132)
  5. Sloan Kettering Institute Postdocs (29)
  6. MSK Grad Students (18)

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People
  1. Christina Crump (12)
  2. Yuan Tian (12)
  3. Christopher Shelton (10)
  4. Kwangwook Ahn (10)
  5. Wan Fung Wong (10)
  6. Georgia Frost (9)

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Years
  1. 2025 (3)
  2. 2024 (2)
  3. 2023 (4)
  4. 2022 (6)
  5. 2021 (2)
  6. 2020 (10)

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Publications
  1. Journal of Biological Chemistry (12)
  2. Proceedings of the National Academy of Sciences of the United States of America (9)
  3. Cancer Research (8)
  4. Biochemistry (5)
  5. Society for Neuroscience Abstract Viewer and Itinerary Planner (4)
  6. ACS Chemical Neuroscience (3)

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Publishers
  1. American Chemical Society (25)
  2. American Association for Cancer Research (12)
  3. American Society for Biochemistry and Molecular Biology (12)
  4. Nature Publishing Group (10)
  5. National Academy of Sciences (9)
  6. Cell Press (6)

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Results (132)

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  • Stereo-controlled synthesis of novel photoreactive γ-secretase inhibitors
    Journal Article

    Yang, G.; Yin, Y. I.; Chun, J.; Shelton, C. C.; Ouerfelli, O.; Li, Y. M.
    Bioorganic & Medicinal Chemistry Letters (2009)

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  • A miniaturized 1536-well format γ-secretase assay
    Journal Article

    Shelton, C. C.; Tian, Y.; Shum, D.; Radu, C.; Djaballah, H.; Li, Y. M.
    Assay and Drug Development Technologies (2009)

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  • Modulation of γ-secretase specificity using small molecule allosteric inhibitors
    Journal Article

    Shelton, C. C.; Zhu, L.; Chau, D.; Yang, L.; Wang, R.; Djaballah, H.; Zheng, H.; Li, Y. M.
    Proceedings of the National Academy of Sciences of the United States of America (2009)

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  • An exo-cell assay for examining real-time γ-secretase activity and inhibition
    Journal Article

    Shelton, C. C.; Tian, Y.; Frattini, M. G.; Li, Y. M.
    Molecular Neurodegeneration (2009)

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  • Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 γ-secretase complexes
    Journal Article

    Placanica, L.; Tarassishin, L.; Yang, G.; Peethumnongsin, E.; Kim, S. H.; Zheng, H.; Sisodia, S. S.; Li, Y. M.
    Journal of Biological Chemistry (2009)

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  • Ligand-dependent notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer
    Journal Article

    Mullendore, M. E.; Koorstra, J. B.; Li, Y. M.; Offerhaus, G. J.; Fan, X.; Henderson, C. M.; Matsui, W.; Eberhart, C. G.; Maitra, A.; Feldmann, G.
    Clinical Cancer Research (2009)

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  • γ-secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity
    Journal Article

    Meng, R. D.; Shelton, C. C.; Li, Y. M.; Qin, L. X.; Notterman, D.; Paty, P. B.; Schwartz, G. K.
    Cancer Research (2009)

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  • The Processing of Human Rhomboid Intramembrane Serine Protease RHBDL2 Is Required for Its Proteolytic Activity
    Journal Article

    Lei, X.; Li, Y. M.
    Journal of Molecular Biology (2009)

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  • Structure and activity of human mitochondrial peptide deformylase, a novel cancer target
    Journal Article

    Escobar-Alvarez, S.; Goldgur, Y.; Yang, G.; Ouerfelli, O.; Li, Y.; Scheinberg, D. A.
    Journal of Molecular Biology (2009)

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  • Interplay of secretases in the amyloid precursor protein processing
    Meeting Abstract

    Tian, Y.; Bassit, B.; Chau, D.; Li, Y.
    Society for Neuroscience Abstract Viewer and Itinerary Planner (2008)

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