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Olivera Grbovic-Huezo

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Meeting Abstract (12)
  2. Journal Article (4)
Groups
  1. GSK Faculty (16)
  2. Molecular Pharmacology and Chemistry Program Faculty (16)
  3. Sloan Kettering Institute Faculty (16)
  4. Sloan Kettering Institute Postdocs (16)
  5. Department of Medicine (15)
  6. Human Oncology and Pathogenesis Program (15)

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People
  1. Neal Rosen (14)
  2. David Solit (13)
  3. Christine Pratilas (9)
  4. Ayana Sawai (7)
  5. Andrea Basso (6)
  6. Agnes Viale (3)

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Years
  1. 2021 (1)
  2. 2020 (1)
  3. 2011 (1)
  4. 2009 (1)
  5. 2007 (4)
  6. 2006 (3)

More Years

Publications
  1. Cancer Research (7)
  2. Clinical Cancer Research (2)
  3. Proceedings of the National Academy of Sciences of the United States of America (2)
  4. Cancer Cell (1)
  5. Communications Biology (1)
  6. EJC Supplements (1)

More Publications

Publishers
  1. American Association for Cancer Research (10)
  2. National Academy of Sciences (2)
  3. American Society of Clinical Oncology (1)
  4. Cell Press (1)
  5. Pergamon-Elsevier Science Ltd (1)
  6. Springer Nature (1)

Results (16)

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  • Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
    Journal Article

    Joshi, S.; Gomes, E. D.; Wang, T.; Corben, A.; Taldone, T.; Gandu, S.; Xu, C.; Sharma, S.; Buddaseth, S.; Yan, P.; more...
    Communications Biology (2021)

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  • Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma
    Journal Article

    Grbovic-Huezo, O.; Pitter, K. L.; Lecomte, N.; Saglimbeni, J.; Askan, G.; Holm, M.; Melchor, J. P.; Chandwani, R.; Joshi, S.; Haglund, C.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2020)

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  • AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity
    Journal Article

    Chandarlapaty, S.; Sawai, A.; Scaltriti, M.; Rodrik-Outmezguine, V. ; Grbovic-Huezo, O.; Serra, V.; Majumder, P. K.; Baselga, J.; Rosen, N.
    Cancer Cell (2011)

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  • Amplification of wild-type BRAF in melanoma is associated with activation of RAF-MEK-ERK signaling and MEK-dependence
    Meeting Abstract

    Blumenthal, E.; Poulikakos, P. I.; Tadi, M.; Grbovic-Huezo, O.; Taylor, B. S.; Janakiraman, M.; Leversha, M.; Viale, A.; Solit, D. B.; Rosen, N.; more...
    Cancer Research (2009)

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  • BRAF mutation predicts MEK-dependence in non-small cell lung cancer (NSCLC)
    Meeting Abstract

    Pratilas, C. A.; Halilovic, E.; Sawai, A.; Grbovic-Huezo, O.; Rosen, N.; Solit, D. B.
    Journal of Clinical Oncology (2007)

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  • Activating mutation in B-RAF disables normal feedback inhibition of MEK and results in increased output of the RAF/MEK/MAPK signaling pathway
    Meeting Abstract

    Pratilas, C. A.; Taylor, B.; Nelander, S.; Grbovic-Huezo, O.; Viale, A.; Solit, D.; Sander, C.; Rosen, N.
    Cancer Research (2007)

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  • BRAF mutation predicts for MEK-dependence in non-small cell lung cancer (NSCLC)
    Meeting Abstract

    Halilovic, E.; Pratilas, C.; Sawai, A.; Grbovic, O.; Rosen, N.; Solit, D. B.
    Cancer Research (2007)

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  • BRAF mutation predicts MEK-dependence in non-small cell lung cancer (NSCLC)
    Meeting Abstract

    Pratilas, C. A.; Halilovic, E.; Persaud, Y.; Sawai, A.; Grbovic-Huezo, O.; Janakiraman, M.; Rosen, N.; Solit, D. B.
    Molecular Cancer Therapeutics (2007)

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  • MAPK activation by B-RAF mutation or tyrosine kinase activation is associated with different patterns of feedback regulation that correlate with functional output of the pathway
    Meeting Abstract

    Pratilas, C. A.; Grbovic, O.; Sebolt-Leopold, J.; Rosen, N.; Solit, D. B.
    Cancer Research (2006)

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  • B-RAF mutation is associated with altered patterns of negative feedback of MAPK signaling that correlate with increased output of the pathway and increased sensitivity to MEK inhibition
    Meeting Abstract

    Pratilas, C.; Grbovic, O.; Zhao, H.; Viale, A.; Solit, D.; Rosen, N.
    EJC Supplements (2006)

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