Synapse - Elisa De Stanchina

Results (11)

Janus kinase inhibition by ruxolitinib extends dasatinib- and dexamethasone-induced remissions in a mouse model of Ph+ ALL

Journal Article

Appelmann, I.; Rillahan, C. D.; de Stanchina, E.; Carbonetti, G.; Chen, C.; Lowe, S. W.; Sherr, C. J.
Blood (2015)

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DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2

Meeting Abstract

Poirier, J.; Gardner, E.; Connis, N.; Moreira, A.; De Stanchina, E.; Hann, C.; Rudin, C. M.
Journal of Thoracic Oncology (2015)

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TP53 and RB1 alterations promote reprogramming and antiandrogen resistance in advanced prostate cancer

Meeting Abstract

Mu, P.; Cao, Z.; Hoover, E.; Wongvipat, J.; Huang, C. H.; Karthaus, W.; Abida, W.; De Stanchina, E.; Sawyers, C.
Cancer Research (2015)

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Human tumorigenesis induced by endogenous DNA transposase

Meeting Abstract

Henssen, A.; Eisenberg, A.; Jiang, E.; Henaff, E.; Koche, R.; Burns, M.; Carson, J. R.; Nanjangud, G.; Still, E.; Gandara, J.; more...
Cancer Research (2015)

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DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2

Journal Article

Poirier, J. T.; Gardner, E. E.; Connis, N.; Moreira, A. L.; de Stanchina, E.; Hann, C. L.; Rudin, C. M.
Oncogene (2015)

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Loss of BAP1 function leads to EZH2-dependent transformation

Journal Article

LaFave, L. M.; Béguelin, W.; Koche, R.; Teater, M.; Spitzer, B.; Chramiec, A.; Papalexi, E.; Keller, M. D.; Hricik, T.; Konstantinoff, K.; more...
Nature Medicine (2015)

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BRAF mutants evade ERK-dependent feedback by different mechanisms that determine their sensitivity to pharmacologic inhibition

Journal Article

Yao, Z.; Torres, N. M.; Tao, A.; Gao, Y.; Luo, L.; Li, Q.; de Stanchina, E.; Abdel-Wahab, O.; Solit, D. B.; Poulikakos, P. I.; more...
Cancer Cell (2015)

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Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ

Journal Article

Schwartz, S.; Wongvipat, J.; Trigwell, C. B.; Hancox, U.; Carver, B. S.; Rodrik-Outmezguine, V. ; Will, M.; Yellen, P.; de Stanchina, E.; Baselga, J.; more...
Cancer Cell (2015)

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Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia

Journal Article

Shih, A. H.; Jiang, Y.; Meydan, C.; Shank, K.; Pandey, S.; Barreyro, L.; Antony-Debre, I.; Viale, A.; Socci, N.; Sun, Y.; more...
Cancer Cell (2015)

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MLN0128, an ATP-competitive mTOR kinase inhibitor with potent in vitro and in vivo antitumor activity, as potential therapy for bone and soft-tissue sarcoma

Journal Article

Slotkin, E. K.; Patwardhan, P. P.; Vasudeva, S. D.; de Stanchina, E.; Tap, W. D.; Schwartz, G. K.
Molecular Cancer Therapeutics (2015)

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