Synapse - David Spriggs

Results (152)

Efficacy of a mitochondrial toxin, F16, in a multi-ATP-depleting regimen plus chemotherapy on human breast cancer (MDA-MB-468) xenografts

Meeting Abstract

Martin, D. S.; Alfieri, A.; Koutcher, J.; Fantin, V.; Spriggs, D.; Norton, L.
Journal of Clinical Oncology (2004)

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Phase I and pharmacokinetic study of VEGF trap administered subcutaneously (sc) to patients (pts) with advanced solid malignancies

Meeting Abstract

Dupont, J.; Schwartz, L.; Koutcher, J.; Spriggs, D.; Gordon, M.; Mendelson, D.; Murren, J.; Lucarelli, A.; Cedarbaum, J.
Journal of Clinical Oncology (2004)

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KOS-862 (Epothilone D): Phase 1 dose escalating and pharmacokinetic (PK) study in patients (pts) with advanced malignancies

Meeting Abstract

Spriggs, D. R.; Dupont, J.; Pezzulli, S.; Larkin, J.; Cropp, G.; Zhou, Y.; Sherrill, M.; Johnson, R. Jr; Hannah, A. L.
EJC Supplements (2003)

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Phase 1 study of CT-2106 (polyglutamate camptothecin) in patients with advanced malingnancies

Meeting Abstract

Sayid, S.; Dupont, J.; McNamara, M.; Doroshow, J. H.; Pezzulli, S.; Spriggs, D.; Eastham, E.; Stromatt, S.; Takimoto, C.
Clinical Cancer Research (2003)

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Phase 1 dose escalating and pharmacokinetic (PK) study of KOS-862 (epothilone D): Phase 2 dose and schedule defined

Meeting Abstract

Spriggs, D.; Dupont, J.; Pezzulli, S.; Larkin, J.; Cropp, G.; Johnson, R.; Hannah, A. L.
Clinical Cancer Research (2003)

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Autoregulation of TNF-alpha in human breast cancer cells: Defining a cis-element in the 3'-UTR RNA of TNF-alpha as the target for HuR binding

Meeting Abstract

Zhao, Z.; Spriggs, D.
Proceedings of the American Association for Cancer Research Annual Meeting (2002)

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Phase 2 study of TLK286 (GST P1-1 Activated Glutathione Analog) in patients with platinum and paclitaxel refractory/resistant advanced epithelial ovarian cancer

Meeting Abstract

Kavanagh, J. J.; Kudelka, A.; Spriggs, D. R.; Bookman, M. A.; Lewis, L.; Maack, C.; Dombroski, J.; Macpherson, J.; Henner, W. D.; Brown, G. L.
European Journal of Cancer (2002)

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A phase I study of the novel high affinity VEGF blocker VEGF trap in patients with refractory solid tumors and lymphoma

Meeting Abstract

Dupont, J.; Pezzulli, S.; Gordon, M.; Mendelson, D.; Murren, J.; Hsu, A.; Holash, J.; Stahl, N.; Cedarbaum, J.; Spriggs, D. R.
European Journal of Cancer (2002)

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Effects of the 3'-untranslated region of human TNF-a and the analogues of thalidomide on the expression of luciferase reporter gene in human epithelial carcinoma cell