Synapse - David Spriggs

Results (11)

Radiopharmacologic screening of antibodies to the unshed ectodomain of MUC16 in ovarian cancer identifies a lead candidate for clinical translation

Journal Article

Nemieboka, B.; Sharma, S. K.; Rao, T. D.; Edwards, K. J.; Yan, S.; Wang, P.; Ragupathi, A.; Piersigilli, A.; Spriggs, D. R.; Lewis, J. S.
Nuclear Medicine and Biology (2020)

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A phase II trial of enzalutamide in patients with androgen receptor positive (AR+) ovarian, primary peritoneal or fallopian tube cancer and one, two, or three prior therapies

Meeting Abstract

Grisham, R. N.; Giri, D. D.; Iasonos, A.; Zhou, Q.; Girshman, J.; McGrath, S. P.; O'Cearbhaill, R. E.; Sabbatini, P.; Tew, W. P.; Hyman, D. M.; more...
Journal of Clinical Oncology (2017)

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Antibodies against specific MUC16 glycosylation sites inhibit ovarian cancer growth

Journal Article

Rao, T. D.; Fernández-Tejada, A.; Axelrod, A.; Rosales, N.; Yan, X.; Thapi, S.; Wang, A.; Park, K. J.; Nemieboka, B.; Xiang, J.; more...
ACS Chemical Biology (2017)

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Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21 days or q28 days) for patients with advanced solid tumors

Journal Article

Hyman, D. M.; Snyder, A. E.; Carvajal, R. D.; Gerecitano, J. F.; Voss, M. H.; Ho, A. L.; Konner, J.; Winkelmann, J. L.; Stasi, M. A.; Monson, K. R.; more...
Cancer Chemotherapy and Pharmacology (2015)

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Phase 1 study of aflibercept administered subcutaneously to patients with advanced solid tumors

Journal Article

Tew, W. P.; Gordon, M.; Murren, J.; Dupont, J.; Pezzulli, S.; Aghajanian, C.; Sabbatini, P.; Mendelson, D.; Schwartz, L.; Gettinger, S.; more...
Clinical Cancer Research (2010)

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A phase I study evaluating the safety and pharmacokinetics of weekly paclitaxel and carboplatin in relapsed ovarian cancer

Journal Article

Leiser, A. L.; Maluf, F. C.; Chi, D. S.; Sabbatini, P.; Hensley, M. L.; Schwartz, L.; Venkatraman, E.; Spriggs, D.; Aghajanian, C.
International Journal of Gynecological Cancer (2007)

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Pharmacodynamic indicators of VEGF trap activity in patients with advanced solid tumors

Meeting Abstract

Lockhart, A. C.; Muruganandham, M.; Schwartz, L.; Koutcher, J.; Donnelly, E.; Andal, R.; Furfine, E. S.; Chevalier, P.; Spriggs, D. R.; Rothenberg, M. L.; more...
Clinical Cancer Research (2005)

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Phase I and pharmacokinetic study of VEGF trap administered subcutaneously (sc) to patients (pts) with advanced solid malignancies

Meeting Abstract

Dupont, J.; Schwartz, L.; Koutcher, J.; Spriggs, D.; Gordon, M.; Mendelson, D.; Murren, J.; Lucarelli, A.; Cedarbaum, J.
Journal of Clinical Oncology (2004)

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Ninety-six-hour paclitaxel infusion after progression during short taxane exposure: A phase II pharmacokinetic and pharmacodynamic study in metastatic breast cancer