Synapse - Carol Aghajanian

Results (615)

Results of an abbreviated phase II study of AKT inhibitor MK-2206 in the treatment of recurrent platinum-resistant high grade serous ovarian, fallopian tube, or primary peritoneal carcinoma (NCT 01283035)

Journal Article

Lee, E. K.; Tan-Wasielewski, Z.; Aghajanian, C.; Coleman, R. L.; Curtis, J.; Hirsch, M. S.; Matulonis, U. A.; Cantley, L. C.; Mills, G. B.; Doyle, L. A.; more...
Gynecologic Oncology Reports (2020)

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Sequential ipilimumab after chemoradiotherapy in curative-intent treatment of patients with node-positive cervical cancer

Journal Article

Mayadev, J. S.; Enserro, D.; Lin, Y. G.; Da Silva, D. M.; Lankes, H. A.; Aghajanian, C.; Ghamande, S.; Moore, K. N.; Kennedy, V. A.; Fracasso, P. M.; more...
JAMA Oncology (2020)

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Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer

Journal Article

Stasenko, M.; Tunnage, I.; Ashley, C. W.; Rubinstein, M. M.; Latham, A. J.; Da Cruz Paula, A.; Mueller, J. J.; Leitao, M. M. Jr; Friedman, C. F.; Makker, V.; more...
Gynecologic Oncology (2020)

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A phase I study of intravenous or intraperitoneal platinum based chemotherapy in combination with veliparib and bevacizumab in newly diagnosed ovarian, primary peritoneal and fallopian tube cancer

Journal Article

Moore, K. N.; Miller, A.; Bell-McGuinn, K. M.; Schilder, R. J.; Walker, J. L.; O'Cearbhaill, R. E.; Guntupalli, S. R.; Armstrong, D. K.; Hagemann, A. R.; Gray, H. J.; more...
Gynecologic Oncology (2020)

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Characteristics and survival of ovarian cancer patients treated with neoadjuvant chemotherapy but not undergoing interval debulking surgery

Journal Article

Liu, Y. L.; Filippova, O. T.; Zhou, Q.; Iasonos, A.; Chi, D. S.; Zivanovic, O.; Sonoda, Y.; Gardner, G. J.; Broach, V. A.; O'Cearbhaill, R. E.; more...
Journal of Gynecologic Oncology (2020)

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Effect of progression-free interval (PFI) following penultimate platinum-based regimen on the efficacy of rucaparib maintenance treatment in patients with platinum-sensitive, recurrent ovarian carcinoma: An analysis from the phase 3 study ARIEL3

Meeting Abstract

Clamp, A. R.; Oza, A. M.; Lorusso, D.; Aghajanian, C.; Oaknin, A.; Dean, A.; Colombo, N.; Weberpals, J. I.; Scambia, G.; Leary, A.; more...
International Journal of Gynecological Cancer (2019)

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Patient-centred outcomes in the phase 3 study ARIEL3 of rucaparib maintenance treatment in patients with platinum-sensitive, recurrent ovarian carcinoma: Post hoc exploratory analyses by BRCA mutation status and patient age

Meeting Abstract

Colombo, N.; Oza, A. M.; Lorusso, D.; Aghajanian, C.; Oaknin, A.; Dean, A.; Weberpals, J. I.; Clamp, A. R.; Scambia, G.; Leary, A.; more...
International Journal of Gynecological Cancer (2019)

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Maintenance olaparib after platinum-based chemotherapy in patients with newly diagnosed advanced ovarian cancer and a BRCA mutation: Efficacy by the timing of surgery and residual tumour status following upfront or interval cytoreductive surgery in the phase III SOLO1 trial

Meeting Abstract

Moore, K.; Colombo, N.; Scambia, G.; Kim, B. G.; Oaknin, A.; Friedlander, M.; Lisyanskaya, A.; Floquet, A.; Leary, A.; Sonke, G. S.; more...
International Journal of Gynecological Cancer (2019)

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Patient-centred outcomes with maintenance olaparib in newly diagnosed patients with advanced ovarian cancer (OC) and a BRCA mutation in the phase III SOLO1 trial to support the clinical benefit of prolongation of progression-free survival (PFS)