Synapse - Philip Adam Friedlander

Philip Adam Friedlander

Research Focus

Former Employee. Graduate Staff; Fellow

Recent additions – View all

V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors
Journal Article

Grbovic, O. M.; Basso, A. D.; Sawai, A.; Ye, Q.; Friedlander, P.; Solit, D.; Rosen, N.
Proceedings of the National Academy of Sciences of the United States of America (2006)

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Treatment of melanoma patients with 17AAG results in downregulation of the MAPK pathway in the melanoma tumors
Meeting Abstract

Friedlander, P.; Solit, D.; Osman, I.; Polsky, D.; Elamparo, R.; Rosen, N.; Chapman, P. B.
Cancer Research (2005)

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Activated, mutated B-raf protein kinase requires the HSP90 chaperone for folding and stability and is degraded in response to HSP90 inhibitors
Meeting Abstract

Grbovic, O. M.; Basso, A. D.; Friedlander, P.; Houghton, A.; Solit, D. B.; Rosen, N.
Cancer Research (2004)

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Co-authors at MSK

3

Rosen
3

Solit
2

Basso
2

Grbovic...
1

Brandst...
1

Chapman
1

Harrison
1

Houghton
1

Kemeny
1

Kraus
1

Mc Kiernan
1

Osman
1

Polsky
1

Polyak
1

Posner
1

Sawai
1

Schwartz
1

Shaha
1

Shah
1

Singh
1

Solan
1

Ye

Types of Work

Publications

Cancer Research (2)
Cancer (1)
Head & Neck (1)
Proceedings of the National Academy of Sciences of the United States of America (1)