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Maria E Caldas Lopes- Vazquez

Formats
  1. Meeting Abstract (25)
  2. Journal Article (14)
Groups
  1. Sloan Kettering Institute Faculty (38)
  2. Center for Hematologic Malignancies (33)
  3. GSK Faculty (33)
  4. Hematologic Malignancies Research (33)
  5. Molecular Pharmacology and Chemistry Program Faculty (33)
  6. Sloan Kettering Institute Postdocs (22)

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People
  1. Gabriela Chiosis (33)
  2. Tony Taldone (18)
  3. Anna Rodina Balingcongan (13)
  4. Malcolm Moore (10)
  5. Jason Lewis (9)
  6. Srikanth Ambati (9)

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Years
  1. 2019 (1)
  2. 2016 (2)
  3. 2015 (4)
  4. 2014 (4)
  5. 2013 (3)
  6. 2012 (3)

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Publications
  1. Cancer Research (12)
  2. Blood (7)
  3. Journal of Clinical Investigation (2)
  4. Abstracts of Papers of the American Chemical Society (1)
  5. Annals of Oncology (1)
  6. Cancer Cell (1)

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Publishers
  1. American Association for Cancer Research (12)
  2. American Society of Hematology (7)
  3. Nature Publishing Group (3)
  4. American Society for Clinical Investigation (2)
  5. Cell Press (2)
  6. American Chemical Society (1)

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Results (39)

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  • YK5 is a novel dual Hsc/Hsp70 inhibitor that is selective for tumor Hsp70 and is a valuable lead for the development of molecules with therapeutic potential in breast cancer
    Meeting Abstract

    Taldone, Tony; Kang, Yanlong; Rodina, Anna; Maharaj, Ronnie; Gozman, Alexander; Cerchietti, Leandro; Wong, Michael J. H.; Baaklini, Imad; Caldas Lopes, Eloisi; Patel, Hardik J.; more...
    Abstracts of Papers of the American Chemical Society (2011)

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  • 124I-PUH71 PET detects upregulated HSP90 breast cancer xenografts
    Meeting Abstract

    Roney, C. A.; Pillarsetty, K.; Caldas-Lopes, E.; Taldone, T.; Chiosis, G.; Lewis, J. S.
    Journal of Nuclear Medicine (2011)

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  • YK5, a novel dual Hsc70 and Hsp70 inhibitor, is selective for tumor Hsp70 and has potent but selective activity in cancer cells
    Meeting Abstract

    Rodina, A.; Kang, Y.; Maharaj, R.; Gozman, A.; Taldone, T.; Cerchietti, L.; Wong, M. J. H.; Baaklini, I.; Caldas-Lopes, E.; Clement, C. C.; more...
    Cancer Research (2010)

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  • The Hsp90 inhibitor PU-H71 is a potent suppressor of metastasis in triple-negative breast cancer models
    Meeting Abstract

    Lopes, E. C.; Bos, P.; Peinado, H.; Cerchietti, L.; Lavotshkin, S.; Melnick, A.; Lyden, D.; Chiosis, G.
    Cancer Research (2010)

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  • Determinants of apoptotic sensitivity to HSP90 inhibition in acute myeloid leukemia
    Meeting Abstract

    Lopes, E. C.; Gozman, A.; Taldone, T.; Ahn, J.; Marubayashi, S.; Rudin, C.; Levine, R. L.; Nimer, S.; Chiosis, G.
    Blood (2010)

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  • HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans
    Journal Article

    Marubayashi, S.; Koppikar, P.; Taldone, T.; Abdel-Wahab, O.; West, N.; Bhagwat, N.; Caldas-Lopes, E.; Ross, K. N.; Gonen, M.; Gozman, A.; more...
    Journal of Clinical Investigation (2010)

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  • Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/ neu expression in mice using (89)Zr-DFO-trastuzumab
    Journal Article

    Holland, J. P.; Caldas-Lopes, E.; Divilov, V.; Longo, V. A.; Taldone, T.; Zatorska, D.; Chiosis, G.; Lewis, J. S.
    PLoS ONE (2010)

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  • BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy
    Journal Article

    Cerchietti, L. C.; Hatzi, K.; Caldas-Lopes, E.; Yang, S. N.; Figueroa, M. E.; Morin, R. D.; Hirst, M.; Mendez, L.; Shaknovich, R.; Cole, P. A.; more...
    Journal of Clinical Investigation (2010)

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  • A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas
    Journal Article

    Cerchietti, L. C.; Lopes, E. C.; Yang, S. N.; Hatzi, K.; Bunting, K. L.; Tsikitas, L. A.; Mallik, A.; Robles, A. I.; Walling, J.; Varticovski, L.; more...
    Nature Medicine (2009)

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  • Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
    Journal Article

    Caldas-Lopes, E.; Cerchietti, L.; Ahn, J. H.; Clement, C. C.; Robles, A. I.; Rodina, A.; Moulick, K.; Taldone, T.; Gozman, A.; Guo, Y.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2009)

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