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Romel Somwar

Formats
  1. Journal Article (59)
  2. Meeting Abstract (47)
  3. Editorial (2)
  4. Research Letter (1)
  5. Review (1)
Groups
  1. Department of Pathology and Laboratory Medicine (110)
  2. Sloan Kettering Institute Postdocs (110)
  3. GSK Faculty (89)
  4. Human Oncology and Pathogenesis Program (85)
  5. Tow Center for Developmental Oncology (TCDO) (85)
  6. Department of Medicine (55)

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People
  1. Marc Ladanyi (85)
  2. Alexander Drilon (38)
  3. Elisa De Stanchina (33)
  4. Marissa Mattar (30)
  5. Gregory Riely (28)
  6. Mark Kris (26)

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Years
  1. 2025 (3)
  2. 2024 (11)
  3. 2023 (6)
  4. 2022 (20)
  5. 2021 (11)
  6. 2020 (5)

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Publications
  1. Journal of Thoracic Oncology (25)
  2. Clinical Cancer Research (15)
  3. Journal of Clinical Oncology (9)
  4. Cancer Research (8)
  5. Cancer Discovery (3)
  6. Disease Models & Mechanisms (3)

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Publishers
  1. American Association for Cancer Research (30)
  2. Elsevier Inc. (28)
  3. American Society of Clinical Oncology (13)
  4. Nature Publishing Group (7)
  5. Nature Research (4)
  6. Oxford University Press (4)

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Results (110)

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  • Allele-specific role of ERBB2 in the oncogenic function of EGFR L861Q in EGFR-mutant lung cancers
    Journal Article

    Sato, H.; Offin, M.; Kubota, D.; Yu, H. A.; Wilhelm, C.; Toyooka, S.; Somwar, R.; Kris, M. G.; Ladanyi, M.
    Journal of Thoracic Oncology (2021)

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  • NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors
    Journal Article

    Somwar, R.; Hofmann, N. E.; Smith, B.; Odintsov, I.; Vojnic, M.; Linkov, I.; Tam, A.; Khodos, I.; Mattar, M. S.; de Stanchina, E.; more...
    Communications Biology (2020)

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  • The anti-HER3 monoclonal antibody seribantumab effectively inhibits growth of patient-derived and isogenic cell line and xenograft models with NRG1 rearrangements
    Meeting Abstract

    Odintsov, I.; Gladstone, E.; Sisso, W. J.; Delasos, L.; Lui, A. J. W.; Sisso, E. M.; Vojnic, M.; Khodos, I.; Mattar, M. S.; de Stanchina, E.; more...
    European Journal of Cancer (2020)

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  • Tumor analyses reveal squamous transformation and off-target alterations as early resistance mechanisms to first-line osimertinib in EGFR-mutant lung cancer
    Journal Article

    Schoenfeld, A. J.; Chan, J. M.; Kubota, D.; Sato, H.; Rizvi, H.; Daneshbod, Y.; Chang, J. C.; Paik, P. K.; Offin, M.; Arcila, M. E.; more...
    Clinical Cancer Research (2020)

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  • MAPK pathway alterations correlate with poor survival and drive resistance to therapy in patients with lung cancers driven by ROS1 fusions
    Journal Article

    Sato, H.; Schoenfeld, A. J.; Siau, E.; Lu, Y. C.; Tai, H.; Suzawa, K.; Kubota, D.; Lui, A. J. W.; Qeriqi, B.; Mattar, M.; more...
    Clinical Cancer Research (2020)

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  • Selectively targeting lung cancer with a novel small molecule that induces lethality through dual inhibition of disulfide reductases
    Meeting Abstract

    Johnson, F. D.; Jansen, S.; Liu, A.; Brandstädter, C.; Lu, D.; Nagelberg, A.; Farnsworth, D.; Sihota, T.; An, J.; Forcina, G. C.; more...
    Journal of Thoracic Oncology (2020)

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  • Generation and characterization of patient-derived preclinical models from tumor cells isolated from cerebrospinal fluid
    Meeting Abstract

    Offin, M.; Vojnic, M.; Liu, Z.; Lui, A.; Siau, E.; Gladstone, E.; Mattar, M.; Khodos, I.; Drilon, A.; Boire, A.; more...
    Neuro-Oncology Advances (2019)

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  • Clinical proof of concept for MCLA-128, a bispecific HER2/3 antibody therapy, in NRG1 fusion-positive cancers
    Meeting Abstract

    Schram, A. M.; O'Reilly, E. M.; Somwar, R.; Benayed, R.; Shameem, S.; Chauhan, T.; Torrisi, J.; Ford, J.; Maussang, D.; Wasserman, E.; more...
    Molecular Cancer Therapeutics (2019)

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  • Elucidating mechanisms of resistance to targeted therapies in mutant EGFR or KRAS driven lung adenocarcinoma harboring dual loss of p53 and RB1
    Meeting Abstract

    Inoue, Y.; Somwar, R.; Ladanyi, M.; Lockwood, W.
    Journal of Thoracic Oncology (2019)

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  • A phase 2 trial of cabozantinib in ROS1-rearranged lung adenocarcinoma
    Meeting Abstract

    Guo, R.; Preeshagul, I.; Schoenfeld, A.; McCarthy, C.; Makhnin, A.; Plodkowski, A.; Ginsberg, M.; Davare, M.; Delasos, L.; Somwar, R.; more...
    Journal of Thoracic Oncology (2019)

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