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Romel Somwar

  1. "Human Oncology and Pathogenesis Program"
Formats
  1. Journal Article (42)
  2. Meeting Abstract (41)
  3. Editorial (1)
  4. Research Letter (1)
Groups
  1. Department of Pathology and Laboratory Medicine (85)
  2. GSK Faculty (85)
  3. Human Oncology and Pathogenesis Program (85)
  4. Sloan Kettering Institute Postdocs (85)
  5. Tow Center for Developmental Oncology (TCDO) (85)
  6. Department of Medicine (53)

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People
  1. Marc Ladanyi (85)
  2. Alexander Drilon (37)
  3. Elisa De Stanchina (33)
  4. Marissa Mattar (30)
  5. Gregory Riely (26)
  6. Inna Khodos (25)

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Years
  1. 2025 (2)
  2. 2024 (10)
  3. 2023 (5)
  4. 2022 (15)
  5. 2021 (11)
  6. 2020 (4)

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Publications
  1. Journal of Thoracic Oncology (20)
  2. Clinical Cancer Research (15)
  3. Journal of Clinical Oncology (9)
  4. Cancer Research (7)
  5. Cancer Discovery (3)
  6. JCO Precision Oncology (3)

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Publishers
  1. American Association for Cancer Research (27)
  2. Elsevier Inc. (22)
  3. American Society of Clinical Oncology (13)
  4. Nature Publishing Group (5)
  5. Oxford University Press (4)
  6. Nature Research (3)

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Results (85)

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  • Overcoming MET-dependent resistance to selective RET inhibition in patients with RET fusion-positive lung cancer by combining selpercatinib with crizotinib
    Journal Article

    Rosen, E. Y.; Johnson, M. L.; Clifford, S. E.; Somwar, R.; Kherani, J. F.; Son, J.; Bertram, A. A.; Davare, M. A.; Gladstone, E.; Ivanova, E. V.; more...
    Clinical Cancer Research (2021)

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  • ROS1 at the crossroads of clinical oncology, molecular diagnostics, and drug development
    Editorial

    Odintsov, I.; Somwar, R.; Ladanyi, M.; Drilon, A.
    JCO Oncology Practice (2021)

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  • Allele-specific role of ERBB2 in the oncogenic function of EGFR L861Q in EGFR-mutant lung cancers
    Journal Article

    Sato, H.; Offin, M.; Kubota, D.; Yu, H. A.; Wilhelm, C.; Toyooka, S.; Somwar, R.; Kris, M. G.; Ladanyi, M.
    Journal of Thoracic Oncology (2021)

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  • NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors
    Journal Article

    Somwar, R.; Hofmann, N. E.; Smith, B.; Odintsov, I.; Vojnic, M.; Linkov, I.; Tam, A.; Khodos, I.; Mattar, M. S.; de Stanchina, E.; more...
    Communications Biology (2020)

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  • The anti-HER3 monoclonal antibody seribantumab effectively inhibits growth of patient-derived and isogenic cell line and xenograft models with NRG1 rearrangements
    Meeting Abstract

    Odintsov, I.; Gladstone, E.; Sisso, W. J.; Delasos, L.; Lui, A. J. W.; Sisso, E. M.; Vojnic, M.; Khodos, I.; Mattar, M. S.; de Stanchina, E.; more...
    European Journal of Cancer (2020)

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  • Tumor analyses reveal squamous transformation and off-target alterations as early resistance mechanisms to first-line osimertinib in EGFR-mutant lung cancer
    Journal Article

    Schoenfeld, A. J.; Chan, J. M.; Kubota, D.; Sato, H.; Rizvi, H.; Daneshbod, Y.; Chang, J. C.; Paik, P. K.; Offin, M.; Arcila, M. E.; more...
    Clinical Cancer Research (2020)

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  • MAPK pathway alterations correlate with poor survival and drive resistance to therapy in patients with lung cancers driven by ROS1 fusions
    Journal Article

    Sato, H.; Schoenfeld, A. J.; Siau, E.; Lu, Y. C.; Tai, H.; Suzawa, K.; Kubota, D.; Lui, A. J. W.; Qeriqi, B.; Mattar, M.; more...
    Clinical Cancer Research (2020)

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  • Generation and characterization of patient-derived preclinical models from tumor cells isolated from cerebrospinal fluid
    Meeting Abstract

    Offin, M.; Vojnic, M.; Liu, Z.; Lui, A.; Siau, E.; Gladstone, E.; Mattar, M.; Khodos, I.; Drilon, A.; Boire, A.; more...
    Neuro-Oncology Advances (2019)

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  • Clinical proof of concept for MCLA-128, a bispecific HER2/3 antibody therapy, in NRG1 fusion-positive cancers
    Meeting Abstract

    Schram, A. M.; O'Reilly, E. M.; Somwar, R.; Benayed, R.; Shameem, S.; Chauhan, T.; Torrisi, J.; Ford, J.; Maussang, D.; Wasserman, E.; more...
    Molecular Cancer Therapeutics (2019)

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  • Elucidating mechanisms of resistance to targeted therapies in mutant EGFR or KRAS driven lung adenocarcinoma harboring dual loss of p53 and RB1
    Meeting Abstract

    Inoue, Y.; Somwar, R.; Ladanyi, M.; Lockwood, W.
    Journal of Thoracic Oncology (2019)

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