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Romel Somwar

  1. "Human Oncology and Pathogenesis Program"
Formats
  1. Journal Article (42)
  2. Meeting Abstract (41)
  3. Editorial (1)
  4. Research Letter (1)
Groups
  1. Department of Pathology and Laboratory Medicine (85)
  2. GSK Faculty (85)
  3. Human Oncology and Pathogenesis Program (85)
  4. Sloan Kettering Institute Postdocs (85)
  5. Tow Center for Developmental Oncology (TCDO) (85)
  6. Department of Medicine (53)

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People
  1. Marc Ladanyi (85)
  2. Alexander Drilon (37)
  3. Elisa De Stanchina (33)
  4. Marissa Mattar (30)
  5. Gregory Riely (26)
  6. Inna Khodos (25)

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Years
  1. 2025 (2)
  2. 2024 (10)
  3. 2023 (5)
  4. 2022 (15)
  5. 2021 (11)
  6. 2020 (4)

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Publications
  1. Journal of Thoracic Oncology (20)
  2. Clinical Cancer Research (15)
  3. Journal of Clinical Oncology (9)
  4. Cancer Research (7)
  5. Cancer Discovery (3)
  6. JCO Precision Oncology (3)

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Publishers
  1. American Association for Cancer Research (27)
  2. Elsevier Inc. (22)
  3. American Society of Clinical Oncology (13)
  4. Nature Publishing Group (5)
  5. Oxford University Press (4)
  6. Nature Research (3)

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Results (85)

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  • Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling
    Journal Article

    Smith, R. S.; Odintsov, I.; Liu, Z.; Lui, A. J. W.; Hayashi, T.; Vojnic, M.; Suehara, Y.; Delasos, L.; Mattar, M. S.; Hmeljak, J.; more...
    Disease Models & Mechanisms (2022)

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  • Functional impact and targetability of PI3KCA, GNAS, and PTEN mutations in a spindle cell rhabdomyosarcoma with MYOD1 L122R mutation
    Journal Article

    Choo, F.; Odinstov, I.; Nusser, K.; Nicholson, K. S.; Davis, L.; Corless, C. L.; Stork, L.; Somwar, R.; Ladanyi, M.; Davis, J. L.; more...
    Cold Spring Harbor Molecular Case Studies (2022)

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  • MYC promotes tyrosine kinase inhibitor resistance in ROS1 fusion positive lung cancers
    Meeting Abstract

    Iyer, S. R.; Odintsov, I.; Schoenfeld, A. J.; Sato, H.; Siau, E.; Drilon, A.; Riely, G. J.; Somwar, R.; Ladanyi, M.; Davare, M. A.
    Cancer Research (2021)

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  • Preclinical activity of seribantumab in gastrointestinal cancers with NRG1 fusions
    Meeting Abstract

    Odintsov, I.; Lui, A. J.; Bloom, P. R.; Vojnic, M.; Leland, S.; Ladanyi, M.; Somwar, R.
    Cancer Research (2021)

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  • The HER2xHER3 bi-specific antibody Zenocutuzumab is effective at blocking growth of tumors driven by NRG1 gene fusions
    Meeting Abstract

    Odintsov, I.; Khodos, I.; Espinosa-Cotton, M.; Lui, A. J.; Mattar, M.; Schram, A. M.; Schackmann, R. C.; Lammerts van Bueren, J.; Geuijen, C. A.; de Stanchina, E.; more...
    Cancer Research (2021)

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  • Novel preclinical patient-derived lung cancer models reveal inhibition of HER3 and MTOR signaling as therapeutic strategies for NRG1 fusion-positive cancers
    Journal Article

    Odintsov, I.; Mattar, M. S.; Lui, A. J. W.; Offin, M.; Kurzatkowski, C.; Delasos, L.; Khodos, I.; Asher, M.; Daly, R. M.; Rekhtman, N.; more...
    Journal of Thoracic Oncology (2021)

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  • Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
    Journal Article

    Inoue, Y.; Nikolic, A.; Farnsworth, D.; Shi, R.; Johnson, F. D.; Liu, A.; Ladanyi, M.; Somwar, R.; Gallo, M.; Lockwood, W. W.
    eLife (2021)

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  • The anti-HER3 mAb seribantumab effectively inhibits growth of patient-derived and isogenic cell line and xenograft models with oncogenic NRG1 fusions
    Journal Article

    Odintsov, I.; Lui, A. J. W.; Sisso, W. J.; Gladstone, E.; Liu, Z.; Delasos, L.; Kurth, R. I.; Sisso, E. M.; Vojnic, M.; Khodos, I.; more...
    Clinical Cancer Research (2021)

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  • Therapeutic potential of NTRK3 inhibition in desmoplastic small round cell tumor
    Journal Article

    Ogura, K.; Somwar, R.; Hmeljak, J.; Magnan, H.; Benayed, R.; Momeni Boroujeni, A.; Bowman, A. S.; Mattar, M. S.; Khodos, I.; de Stanchina, E.; more...
    Clinical Cancer Research (2021)

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  • RET inhibition in novel patient-derived models of RET fusion-positive lung adenocarcinoma reveals a role for MYC upregulation
    Journal Article

    Hayashi, T.; Odintsov, I.; Smith, R. S.; Ishizawa, K.; Liu, A. J. W.; Delasos, L.; Kurzatkowski, C.; Tai, H.; Gladstone, E.; Vojnic, M.; more...
    Disease Models & Mechanisms (2021)

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