Synapse - Ross Levine

Results (774)

Cohesin mutations in myeloid malignancies made simple

Journal Article

Viny, A. D.; Levine, R. L.
Current Opinion in Hematology (2018)

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome-like acute B-cell lymphoblastic leukemia

Journal Article

Zhang, Q.; Shi, C.; Han, L.; Jain, N.; Roberts, K. G.; Ma, H.; Cai, T.; Cavazos, A.; Tabe, Y.; Jacamo, R. O.; more...
Oncotarget (2018)

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JAK2/IDH-mutant–driven myeloproliferative neoplasm is sensitive to combined targeted inhibition

Journal Article

McKenney, A. S.; Lau, A. N.; Hanasoge Somasundara, A. V.; Spitzer, B.; Intlekofer, A. M.; Ahn, J.; Shank, K.; Rapaport, F. T.; Patel, M. A.; Papalexi, E.; more...
Journal of Clinical Investigation (2018)

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Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms

Journal Article

Hobbs, G. S.; Hanasoge Somasundara, A. V.; Kleppe, M.; Litvin, R.; Arcila, M.; Ahn, J.; McKenney, A. S.; Knapp, K.; Ptashkin, R.; Weinstein, H.; more...
Haematologica (2018)

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Spliceosomal dysfunction Is a critical mediator of IDH2 mutant leukemogenesis

Meeting Abstract

Yoshimi, A.; Lin, K. T.; Wiseman, D.; Intlekofer, A. M.; Wang, B.; Pastore, A.; Rahman, M.; Lee, S. C. W.; Liu, B.; Micol, J. B.; more...
Blood (2017)

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PHF6 mutations defines a subgroup of mixed phenotype of acute leukemia with aberrant T-cell differentiation

Meeting Abstract

Xiao, W.; Pastore, F.; Getta, B.; Hultquist, A.; Shaffer, B. C.; Giralt, S. A.; Rampal, R. K.; Arcila, M. E.; Levine, R. L.; Roshal, M.
Blood (2017)

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Genomic landscapes in elderly AML

Meeting Abstract

Rapaport, F.; Baslan, T.; Wang, L.; Sheridan, C.; Lee, T.; Hricik, T.; de Massy, M. R.; Telis, L.; Neelamraju, Y.; Medina, J.; more...
Blood (2017)

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Population-scale identification of clonal hematopoiesis derived mutations in solid tumor mutation profiling

Meeting Abstract

Ptashkin, R.; Coombs, C. C.; Hyman, D. M.; Solit, D.; Baselga, J.; Arcila, M. E.; Ladanyi, M.; Levine, R. L.; Berger, M. F.; Zehir, A.
Blood (2017)

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Clonal heterogeneity in differentiation response and resistance to the IDH2 inhibitor enasidenib in acute myeloid leukemia

Meeting Abstract

Quek, L.; David, M.; Kennedy, A.; Metzner, M.; Amatangelo, M.; Shih, A. H.; Stoilova, B.; Karamitros, D.; Quivoron, C.; Heiblig, M.; more...
Blood (2017)

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SETBP1 and NRAS mutations are frequent events in post-myeloproliferative neoplasm acute myeloid leukemia (post-MPN AML) lacking JAK-STAT activating mutations

Meeting Abstract

Menghrajani, K.; Rapaport, F.; McNamara, C. J.; Devlin, S. M.; Famulare, C.; Patel, M.; Medina, J.; Sandy, L.; Kosiorek, H.; Singer Weinberg, R.; more...
Blood (2017)

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