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Ross Levine

  1. "Cancer Biology and Genetics Program Faculty"
Formats
  1. Journal Article (19)
  2. Meeting Abstract (9)
  3. Research Letter (1)
Groups
  1. Adult Leukemia (29)
  2. Cancer Biology and Genetics Program Faculty (29)
  3. Center for Hematologic Malignancies (29)
  4. Department of Medicine (29)
  5. Executive Committee, Center for Hematologic Malignancies (29)
  6. GSK Faculty (29)

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People
  1. Craig Thompson (16)
  2. Omar Abdel-Wahab (10)
  3. Scott Lowe (10)
  4. Alan Shih (8)
  5. Martin Tallman (8)
  6. Patrick Ward (8)

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Years
  1. 2024 (2)
  2. 2022 (1)
  3. 2021 (2)
  4. 2020 (1)
  5. 2019 (1)
  6. 2018 (2)

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Publications
  1. Blood (7)
  2. Nature (4)
  3. Cancer Discovery (3)
  4. Cancer Cell (2)
  5. Cell Reports (2)
  6. Cancer Research (1)

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Publishers
  1. Nature Publishing Group (9)
  2. American Society of Hematology (7)
  3. American Association for Cancer Research (4)
  4. Cell Press (4)
  5. American Society for Biochemistry and Molecular Biology (1)
  6. American Society for Clinical Investigation (1)

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Results (29)

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  • DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia
    Journal Article

    Rampal, R.; Alkalin, A.; Madzo, J.; Vasanthakumar, A.; Pronier, E.; Patel, J.; Li, Y.; Ahn, J.; Abdel-Wahab, O.; Shih, A.; more...
    Cell Reports (2014)

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  • A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia
    Journal Article

    Shah, S.; Schrader, K. A.; Waanders, E.; Timms, A. E.; Vijai, J.; Miething, C.; Wechsler, J.; Yang, J.; Hayes, J.; Klein, R. J.; more...
    Nature Genetics (2013)

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  • The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization
    Journal Article

    Ward, P. S.; Lu, C.; Cross, J. R.; Abdel-Wahab, O.; Levine, R. L.; Schwartz, G. K.; Thompson, C. B.
    Journal of Biological Chemistry (2013)

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  • Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production
    Journal Article

    Ward, P. S.; Cross, J. R.; Lu, C.; Weigert, O.; Abdel-Wahab, O.; Levine, R. L.; Weinstock, D. M.; Sharp, K. A.; Thompson, C. B.
    Oncogene (2012)

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  • IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
    Journal Article

    Turcan, S.; Rohle, D.; Goenka, A.; Walsh, L. A.; Fang, F.; Yilmaz, E.; Campos, C.; Fabius, A. W. M.; Lu, C.; Ward, P. S.; more...
    Nature (2012)

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  • IDH mutation impairs histone demethylation and results in a block to cell differentiation
    Journal Article

    Lu, C.; Ward, P. S.; Kapoor, G. S.; Rohle, D.; Turcan, S.; Abdel-Wahab, O.; Edwards, C. R.; Khanin, R.; Figueroa, M. E.; Melnick, A.; more...
    Nature (2012)

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  • Epigenetic effects of IDH1/IDH2 mutations
    Meeting Abstract

    Melnick, A. M.; Levine, R. L.; Figueroa, M. E.; Thompson, C. B.; Abdel-Wahab, O.
    Blood (2011)

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  • The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting α-ketoglutarate to 2-hydroxyglutarate
    Journal Article

    Ward, P. S.; Patel, J.; Wise, D. R.; Abdel-Wahab, O.; Bennett, B. D.; Coller, H. A.; Cross, J. R.; Fantin, V. R.; Hedvat, C. V.; Perl, A. E.; more...
    Cancer Cell (2010)

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  • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
    Journal Article

    Figueroa, M. E.; Abdel-Wahab, O.; Lu, C.; Ward, P. S.; Patel, J.; Shih, A.; Li, Y.; Bhagwat, N.; Vasanthakumar, A.; Fernandez, H. F.; more...
    Cancer Cell (2010)

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