Synapse - David Hyman

Results (57)

Genomic landscape and clinical features of carcinomas with ERBB2 S310 extracellular domain mutations

Meeting Abstract

Desmeules, P.; Zehir, A.; Hyman, D. M.; Arcila, M. E.
Laboratory Investigation (2017)

Pan-TRK IHC is an efficient and reliable screening assay for targetable NTRK fusions

Meeting Abstract

Hechtman, J. F.; Drilon, A.; Hyman, D. M.; Zehir, A.; Dogan, S.; Arcila, M. E.; Ladanyi, M.; Benayed, R.; Jungbluth, A.
Laboratory Investigation (2017)

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Next-generation assessment of human growth factor receptor 2 (ERBB2) amplification status: Clinical validation in the context of a hybrid capture-based, comprehensive solid tumor genomic profiling assay

Journal Article

Ross, D. S.; Zehir, A.; Cheng, D. T.; Benayed, R.; Nafa, K.; Hechtman, J. F.; Janjigian, Y. Y.; Weigelt, B.; Razavi, P.; Hyman, D. M.; more...
Journal of Molecular Diagnostics (2017)

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Prevalence of clonal hematopoiesis in patients with advanced cancer

Meeting Abstract

Zehir, A.; Coombs, C. C.; Devlin, S.; Kishtagari, A.; Hyman, D. M.; Solit, D. B.; Robson, M. E.; Baselga, J.; Arcila, M. E.; Tallman, M. S.; more...
Journal of Clinical Oncology (2016)

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Next generation sequencing (NGS) in lung adenocarcinoma (LA) as a guide to treatment selection

Meeting Abstract

Jordan, E.; Barron, D.; Schultz, N.; Chakravarty, D.; Kris, M. G.; Rudin, C. M.; Li, B. T.; Yu, H. A.; Drilon, A. E.; Rusch, V. W.; more...
Journal of Clinical Oncology (2016)

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Mutational analysis of clonal hematopoiesis in solid tumor patients illustrates the critical role of systemic anti-cancer therapies in the evolution of somatic leukemia disease alleles

Meeting Abstract

Coombs, C. C.; Zehir, A.; Devlin, S.; Kishtagari, A.; Hyman, D. M.; Solit, D.; Robson, M.; Baselga, J.; Arcila, M.; Tallman, M. S.; more...
Blood (2016)

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Genomic characterization of primary and metastatic prostate cancer (PC) using a targeted next-generation sequencing assay

Meeting Abstract

Abida, W.; Brennan, R.; Armenia, J.; Curtis, K. R.; Gopalan, A.; Arcila, M. E.; Danila, D. C.; Rathkopf, D. E.; Morris, M. J.; Slovin, S. F.; more...
Journal of Clinical Oncology (2016)

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Germline variants in targeted tumor sequencing using matched normal DNA

Journal Article

Schrader, K. A.; Cheng, D. T.; Joseph, V.; Prasad, M.; Walsh, M.; Zehir, A.; Ni, A.; Thomas, T.; Benayed, R.; Ashraf, A.; more...
JAMA Oncology (2016)

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What hides behind the MASC: Clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC)

Journal Article

Drilon, A.; Li, G.; Dogan, S.; Gounder, M.; Shen, R.; Arcila, M.; Wang, L.; Hyman, D. M.; Hechtman, J.; Wei, G.; more...
Annals of Oncology (2016)

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Identification of targetable kinase alterations in patients with colorectal carcinoma that are preferentially associated with wild-type RAS/RAF

Journal Article

Hechtman, J. F.; Zehir, A.; Yaeger, R.; Wang, L.; Middha, S.; Zheng, T.; Hyman, D. M.; Solit, D.; Arcila, M. E.; Borsu, L.; more...
Molecular Cancer Research (2016)

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