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David Hyman

  1. "Eileen O'Reilly"
Formats
  1. Meeting Abstract (7)
  2. Journal Article (4)
  3. Research Letter (1)
Groups
  1. Center for Pancreatic Cancer Research (12)
  2. Department of Medicine (12)
  3. Early Drug Development Service (12)
  4. Gastrointestinal Oncology Service (12)
  5. Solid Tumor Oncology Division (12)
  6. Department of Pathology and Laboratory Medicine (11)

More Groups

People
  1. Eileen O'Reilly (12)
  2. Michael Berger (10)
  3. Ahmet Zehir (8)
  4. David Solit (8)
  5. David Klimstra (7)
  6. Leonard Saltz (7)

More People

Years
  1. 2019 (5)
  2. 2018 (1)
  3. 2017 (3)
  4. 2016 (3)
Publications
  1. Journal of Clinical Oncology (5)
  2. Clinical Cancer Research (2)
  3. Annals of Oncology (1)
  4. Cancer Research (1)
  5. JAMA - Journal of the American Medical Association (1)
  6. Molecular Cancer Therapeutics (1)

More Publications

Publishers
  1. American Society of Clinical Oncology (5)
  2. American Association for Cancer Research (4)
  3. American Medical Association (1)
  4. Nature Publishing Group (1)
  5. Oxford University Press (1)

Results (12)

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  • Clinical proof of concept for MCLA-128, a bispecific HER2/3 antibody therapy, in NRG1 fusion-positive cancers
    Meeting Abstract

    Schram, A. M.; O'Reilly, E. M.; Somwar, R.; Benayed, R.; Shameem, S.; Chauhan, T.; Torrisi, J.; Ford, J.; Maussang, D.; Wasserman, E.; more...
    Molecular Cancer Therapeutics (2019)

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  • A phase II basket study of MCLA-128, a bispecific antibody targeting the HER3 pathway, in NRG1 fusion-positive advanced solid tumours
    Meeting Abstract

    Schram, A. M.; Drilon, A.; Macarulla Mercade, T.; O'Reilly, E. M.; Rodon, J. A.; Wolpin, B. M.; Ou, S. H. I.; Kim, D. W.; Yang, J. C. H.; Lam, Y. C. J.; more...
    Annals of Oncology (2019)

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  • BRCA-mediated tumorigenesis is origin and cell-type dependent
    Meeting Abstract

    Jonsson, P.; Cheng, M. L.; Bandlamudi, C.; Srinivasan, P.; Chavan, S. S.; Friedman, N. D.; Rosen, E. Y.; Richards, A. L.; Bouvier, N.; Selcuklu, S. D.; more...
    Cancer Research (2019)

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  • Tumour lineage shapes BRCA-mediated phenotypes
    Research Letter

    Jonsson, P.; Bandlamudi, C.; Cheng, M. L.; Srinivasan, P.; Chavan, S. S.; Friedman, N. D.; Rosen, E. Y.; Richards, A. L.; Bouvier, N.; Selcuklu, S. D.; more...
    Nature (2019)

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  • Microsatellite instability is associated with the presence of Lynch syndrome pan-cancer
    Journal Article

    Latham, A.; Srinivasan, P.; Kemel, Y.; Shia, J.; Bandlamudi, C.; Mandelker, D.; Middha, S.; Hechtman, J.; Zehir, A.; Dubard-Gault, M.; more...
    Journal of Clinical Oncology (2019)

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  • Comprehensive molecular profiling of intrahepatic and extrahepatic cholangiocarcinomas: Potential targets for intervention
    Journal Article

    Lowery, M. A.; Ptashkin, R.; Jordan, E.; Berger, M. F.; Zehir, A.; Capanu, M.; Kemeny, N. E.; O'Reilly, E. M.; El-Dika, I.; Jarnagin, W. R.; more...
    Clinical Cancer Research (2018)

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  • A prospective analysis of germline alterations (GA) in biliary tract cancer (BTC)
    Meeting Abstract

    Lowery, M. A.; Jordan, E.; Kemel, Y.; Mukherjee, S.; Cercek, A.; Kemeny, N. E.; Varghese, A. M.; Rusek, M.; Boucher, T. M.; Mandelker, D.; more...
    Journal of Clinical Oncology (2017)

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  • Real-time genomic profiling of pancreatic ductal adenocarcinoma: Potential actionability and correlation with clinical phenotype
    Journal Article

    Lowery, M. A.; Jordan, E. J.; Basturk, O.; Ptashkin, R. N.; Zehir, A.; Berger, M. F.; Leach, T.; Herbst, B.; Askan, G.; Maynard, H.; more...
    Clinical Cancer Research (2017)

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  • Mutation detection in patients with advanced cancer by universal sequencing of cancer-related genes in tumor and normal DNA vs guideline-based germline testing
    Journal Article

    Mandelker, D.; Zhang, L.; Kemel, Y.; Stadler, Z. K.; Joseph, V.; Zehir, A.; Pradhan, N.; Arnold, A.; Walsh, M. F.; Li, Y.; more...
    JAMA - Journal of the American Medical Association (2017)

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  • Comprehensive molecular profiling and analysis of mutual exclusivity of genetic aberrations (MEGA) of intra- and extrahepatic cholangiocarcinomas (IHC and EHC) evaluation of prognostic features and potential targets for intervention
    Meeting Abstract

    Lowery, M. A.; Ptashkin, R.; Jordan, E.; Berger, M. F.; Zehir, A.; Kemeny, N. E.; O'Reilly, E. M.; Jarnagin, W. R.; Harding, J. J.; DeMatteo, R. P.; more...
    Journal of Clinical Oncology (2016)

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