Synapse - Sarat Chandarlapaty

Results (90)

A phase II study of fulvestrant plus abemaciclib in hormone receptor–positive advanced or recurrent endometrial cancer

Journal Article

Green, A. K.; Zhou, Q.; Iasonos, A.; Zammarrelli, W. A. 3rd; Weigelt, B.; Ellenson, L. H.; Chhetri-Long, R.; Shah, P.; Loh, J.; Hom, V.; more...
Clinical Cancer Research (2025)

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A genomics-driven artificial intelligence–based model classifies breast invasive lobular carcinoma and discovers CDH1 inactivating mechanisms

Journal Article

Pareja, F.; Dopeso, H.; Wang, Y. K.; Gazzo, A. M.; Brown, D. N.; Banerjee, M.; Selenica, P.; Bernhard, J. H.; Derakhshan, F.; da Silva, E. M.; more...
Cancer Research (2024)

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ESR1 F404 mutations and acquired resistance to fulvestrant in ESR1-mutant breast cancer

Journal Article

Kingston, B.; Pearson, A.; Herrera-Abreu, M. T.; Sim, L. X.; Cutts, R. J.; Shah, H.; Moretti, L.; Kilburn, L. S.; Johnson, H.; Macpherson, I. R.; more...
Cancer Discovery (2024)

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A druggable FOXA1-glucocorticoid receptor transcriptional axis drives tumor growth in a subset of non-small cell lung cancer

Journal Article

Dorso, M.; Patel, P. T.; Pankov, A.; Boyer, J. A.; Soni, R. K.; Del Priore, I. S.; Hayatt, O.; Kulick, A.; Hagen, C. J.; de Stanchina, E.; more...
Cancer Research Communications (2023)

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An open-label phase I study of GDC-0927 in postmenopausal women with locally advanced or metastatic estrogen receptor–positive breast cancer

Journal Article

Chandarlapaty, S.; Dickler, M. N.; Perez Fidalgo, J. A.; Villanueva-Vázquez, R.; Giltnane, J.; Gates, M.; Chang, C. W.; Cheeti, S.; Fredrickson, J.; Wang, X.; more...
Clinical Cancer Research (2023)

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ADCs or: How I learned to stop worrying and love chemotherapy

Editorial

Gupta, A.; Drago, J. Z.; Chandarlapaty, S.
Cancer Discovery (2023)

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Amcenestrant, an oral selective estrogen receptor (ER) degrader (SERD), in ER+/HER2-advanced breast cancer (aBC): Combined biomarker analyses from a phase 1/2 study in postmenopausal women and a phase 1 study in postmenopausal Japanese women

Meeting Abstract

Iwata, H.; Bardia, A.; Lord, S.; Linden, H. M.; Campone, M.; Tamura, K.; Yonemori, K.; Mukohara, T.; Combeau, C.; Ternes, N.; more...
Cancer Research (2022)

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Estrogen receptor expression and ER dependent breast tumor growth are dependent on translation initiation factor EIF4A

Meeting Abstract

Boyer, J. A.; Dorso, M. A.; Amor, C.; Reiter, J.; Xu, J.; de Stanchina, E.; Wendel, H. G.; Chandarlapaty, S.; Rosen, N.
Cancer Research (2022)

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NR2F2 mediates cell growth and endocrine resistance in NF1 loss, ER+ breast cancer

Meeting Abstract

Cai, Y.; Zhao, P.; Wu, F.; Shao, H.; Razavi, P.; Xu, G.; Scaltriti, M.; Chandarlapaty, S.
Cancer Research (2022)

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Statin therapy enhances the efficacy of HER2 directed antibody-drug conjugates in breast cancer

Meeting Abstract

Liu, B.; Drago, J. Z.; Rao, Y.; Pereira, P. R.; Safonov, A.; Marra, A.; Ahmed, M. S.; Modi, S.; Reis, J. S.; Montemurro, F.; more...
Cancer Research (2022)

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