Synapse - Gregory Riely

Results (219)

Clinical and genomic predictors of response and toxicity to sotorasib in a real-world cohort of patients with advanced KRAS G12C-mutant non-small cell lung cancer

Meeting Abstract

Arbour, K. C.; Thummalapalli, R.; Bernstein, E.; Herzberg, B.; Li, B. T.; Iqbal, A.; Santini, F. C.; Eng, J.; Ladanyi, M.; Yang, S. R.; more...
Journal of Clinical Oncology (2023)

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Large-scale clinicogenomic models of solid tumor CNS metastasis

Meeting Abstract

Jee, J.; Luthra, A.; Fong, C.; Pichotta, K.; Tran, T.; Altoe, M.; Miller, A.; Shen, R.; Berger, M. F.; Sanchez-Vega, F.; more...
Journal of Clinical Oncology (2023)

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Combination therapy with MDM2 and MEK inhibitors is effective in patient-derived models of lung adenocarcinoma with concurrent oncogenic drivers and MDM2 amplification

Journal Article

Elkrief, A.; Odintsov, I.; Markov, V.; Caeser, R.; Sobczuk, P.; Tischfield, S. E.; Bhanot, U.; Vanderbilt, C. M.; Cheng, E. H.; Drilon, A.; more...
Journal of Thoracic Oncology (2023)

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Efficacy of PD-(L)1 blockade monotherapy compared with PD-(L)1 blockade plus chemotherapy in first-line PD-L1-positive advanced lung adenocarcinomas: A cohort study

Journal Article

Elkrief, A.; Alessi, J. M. V.; Ricciuti, B.; Brown, S.; Rizvi, H.; Preeshagul, I. R.; Wang, X.; Pecci, F.; Di Federico, A.; Lamberti, G.; more...
Journal for ImmunoTherapy of Cancer (2023)

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Genomic mapping of metastatic organotropism in lung adenocarcinoma

Journal Article

Lengel, H. B.; Mastrogiacomo, B.; Connolly, J. G.; Tan, K. S.; Liu, Y.; Fick, C. N.; Dunne, E. G.; He, D.; Lankadasari, M. B.; Satravada, B. A.; more...
Cancer Cell (2023)

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Brief report: Combination of osimertinib and dacomitinib to mitigate primary and acquired resistance in EGFR-mutant lung adenocarcinomas

Journal Article

Elkrief, A.; Makhnin, A.; Moses, K. A.; Ahn, L. S.; Preeshagul, I. R.; Iqbal, A. N.; Hayes, S. A.; Plodkowski, A. J.; Paik, P. K.; Ladanyi, M.; more...
Clinical Cancer Research (2023)

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Molecular biomarkers of disease outcomes and mechanisms of acquired resistance to first-line osimertinib in advanced EGFR-mutant lung cancers

Journal Article

Choudhury, N. J.; Marra, A.; Sui, J. S. Y.; Flynn, J.; Yang, S. R.; Falcon, C. J.; Selenica, P.; Schoenfeld, A. J.; Rekhtman, N.; Gomez, D.; more...
Journal of Thoracic Oncology (2023)

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Molecular characterization of acquired resistance to KRAS(G12C)–EGFR inhibition in colorectal cancer

Journal Article

Yaeger, R.; Mezzadra, R.; Sinopoli, J.; Bian, Y.; Marasco, M.; Kaplun, E.; Gao, H.; Zhao, H. Y.; Paula, A. D. C.; Zhu, Y.; more...
Cancer Discovery (2023)

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SRC family kinase inhibition targets YES1 and YAP1 as primary drivers of lung cancer and as mediators of acquired resistance to ALK and epidermal growth factor receptor inhibitors