Synapse - Jamie Chaft

Results (289)

Phase I trial of the TNF-α inhibitor certolizumab plus chemotherapy in stage IV lung adenocarcinomas

Journal Article

Paik, P. K.; Luo, J.; Ai, N.; Kim, R.; Ahn, L.; Biswas, A.; Coker, C.; Ma, W.; Wong, P.; Buonocore, D. J.; more...
Nature Communications (2022)

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Phase II NAUTIKA1 study of targeted therapies in stage II-III NSCLC: Preliminary data of neoadjuvant alectinib for ALK+ NSCLC

Meeting Abstract

Lee, J. M.; Sepesi, B.; Toloza, E. M.; Pass, H. I.; Lin, J.; Johnson, B. E.; Heymach, J. V.; Johnson, M. L.; Ding, B.; Schulze, K.; more...
Journal of Thoracic Oncology (2022)

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Planned interim analysis of a phase II trial of concurrent durvalumab and radiation therapy for locally advanced lung cancer

Meeting Abstract

Rimner, A.; Fitzgerald, K.; Iqbal, A. N.; Shepherd, A. F.; Gomez, D. R.; Shin, J. Y.; Gelblum, D. Y.; Hajj, C.; Albrecht, F.; Kotecha, R. R.; more...
Journal of Thoracic Oncology (2022)

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T-cell dynamics in response to neoadjuvant atezolizumab in early NSCLC by antigen response and T-cell receptor sequencing

Meeting Abstract

Oezkan, F.; Hilz, S.; Grindheim, J.; Wallace, A.; Seweryn, M.; Reuben, A.; Zhang, J.; Owen, D. H.; Nicholas, A.; Yadav, M.; more...
Journal of Thoracic Oncology (2022)

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Biomarkers associated with pulmonary exacerbations in a prospective, placebo-controlled, randomized trial of nintedanib for the treatment of radiation pneumonitis

Meeting Abstract

Moore, Z. R.; Huang, X.; Lobaugh, S.; Geyer, A.; Gelblum, D.; Shepherd, A. F.; Shaverdian, N.; Wu, A. J.; Chaft, J.; Zauderer, M.; more...
International Journal of Radiation Oncology, Biology, Physics (2022)

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NAUTIKA1: A multicenter phase II study with a PD-L1+ cohort of patients receiving atezolizumab (atezo) with low-dose stereotactic body radiation therapy (SBRT) as neoadjuvant therapy for resectable stage IB-III NSCLC

Meeting Abstract

Tian, S.; Kozono, D. E.; Ohri, N.; Jolly, S.; Johnson, B. E.; Chaft, J.; Toloza, E. M.; Ding, B.; Ngiam, C.; Schulz, K.; more...
International Journal of Radiation Oncology, Biology, Physics (2022)

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Patterns of failure in resectable stage I-IIIA NSCLC treated with neoadjuvant immunotherapy combinations, a secondary analysis of a prospective trial

Meeting Abstract

Mao, S.; Rosner, S.; Forde, P.; Chaft, J.; Jones, D.; Spicer, J.; Hales, R. K.; Ha, J.; Hu, C.; Voong, R.
International Journal of Radiation Oncology, Biology, Physics (2022)

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Tumor mutational burden predicts progression-free survival and local-regional control in locally advanced non-small cell lung cancer patients treated with chemoradiation and durvalumab

Meeting Abstract

Shaverdian, N.; Shepherd, A. F.; Offin, M.; Gelblum, D.; Wu, A. J.; Simone, C. B. 2nd; Schoenfeld, A. J.; Jones, D.; Rimner, A.; Chaft, J.; more...
International Journal of Radiation Oncology, Biology, Physics (2022)

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Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors