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Alan H Shih

  1. "Center for Molecular Imaging and Biotechnology"
Formats
  1. Journal Article (16)
  2. Meeting Abstract (12)
Groups
  1. Adult Leukemia (28)
  2. Center for Hematologic Malignancies (28)
  3. Center for Molecular Imaging and Biotechnology (28)
  4. Department of Medicine (28)
  5. Executive Committee, Center for Hematologic Malignancies (28)
  6. GSK Faculty (28)

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People
  1. Ross Levine (28)
  2. Franck Rapaport (8)
  3. Kaitlyn Shank (7)
  4. Abbas Nazir (5)
  5. Eytan Stein (5)
  6. Martin Tallman (4)

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Years
  1. 2023 (1)
  2. 2020 (2)
  3. 2018 (4)
  4. 2017 (5)
  5. 2016 (3)
  6. 2015 (3)

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Publications
  1. Blood (11)
  2. Cancer Cell (3)
  3. Cancer Discovery (3)
  4. Nature (2)
  5. Annals of Hematology (1)
  6. Cancer Research (1)

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Publishers
  1. American Society of Hematology (11)
  2. Cell Press (5)
  3. American Association for Cancer Research (4)
  4. Nature Publishing Group (3)
  5. Elsevier Inc. (1)
  6. Elsevier Science, Inc. (1)

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Results (28)

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  • Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells
    Journal Article

    Kunimoto, H.; McKenney, A. S.; Meydan, C.; Shank, K.; Nazir, A.; Rapaport, F.; Durham, B.; Garrett-Bakelman, F. E.; Pronier, E.; Shih, A. H.; more...
    Blood (2017)

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  • Combination targeted therapy to disrupt aberrant oncogenic signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia
    Journal Article

    Shih, A. H.; Meydan, C.; Shank, K.; Garrett-Bakelman, F. E.; Ward, P. S.; Intlekofer, A. M.; Nazir, A.; Stein, E. M.; Knapp, K.; Glass, J.; more...
    Cancer Discovery (2017)

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  • Cooperative epigenetic remodeling by TET2 loss and NRAS mutation drives myeloid transformation and MEK inhibitor sensitivity
    Meeting Abstract

    Kunimoto, H.; Meydan, C.; Nazir, A.; Shank, K.; Maher, R.; Rapaport, F.; Pronier, E.; Melnick, A.; Levine, R. L.; Shih, A. H.
    Blood (2016)

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  • A highly sensitive and robust method for genome-wide 5hmC profiling of rare cell populations
    Journal Article

    Han, D.; Lu, X.; Shih, A. H.; Nie, J.; You, Q.; Xu, M. M.; Melnick, A. M.; Levine, R. L.; He, C.
    Molecular Cell (2016)

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  • Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles
    Journal Article

    Hatlen, M. A.; Arora, K.; Vacic, V.; Grabowska, E. A.; Liao, W.; Riley-Gillis, B.; Oschwald, D. M.; Wang, L.; Joergens, J. E.; Shih, A. H.; more...
    Journal of Experimental Medicine (2016)

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  • Integrative analysis of the mutational landscape of mouse and human AML identifies functionally relevant leukemia disease alleles
    Meeting Abstract

    Hatlen, M. A.; Arora, K.; Vacic, V.; Grabowska, E. A.; Liao, W.; Riley-Gillis, B.; Oschwald, D. M.; Wang, L.; Joergens, J. E.; Shih, A. H.; more...
    Blood (2015)

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  • Significance of novel gene mutations in AML
    Meeting Abstract

    Shih, A.; Jiang, Y.; Meydan, C.; Melnick, A.; Levine, R.
    Annals of Hematology (2015)

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  • Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia
    Journal Article

    Shih, A. H.; Jiang, Y.; Meydan, C.; Shank, K.; Pandey, S.; Barreyro, L.; Antony-Debre, I.; Viale, A.; Socci, N.; Sun, Y.; more...
    Cancer Cell (2015)

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  • AG-221, a small molecule mutant IDH2 inhibitor, remodels the epigenetic state of IDH2-mutant cells and induces alterations in self-renewal/differentiation in IDH2-mutant AML model in vivo
    Meeting Abstract

    Shih, A. H.; Shank, K. R.; Meydan, C.; Intlekofer, A. M.; Ward, P.; Thompson, C. B.; Melnick, A. M.; Travins, J.; Straley, K.; Gliser, C.; more...
    Blood (2014)

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  • Mutation profiling of therapy-related myeloid neoplasms using next-generation sequencing demonstrates distinct profiles from de novo disease
    Meeting Abstract

    Shih, A. H.; Rapaport, F.; Chung, S. S.; Dolezal, E. K.; Hobson, S.; Amato, M. K.; Park, C. Y.; Sekeres, M. A.; van den Brink, M. R. M.; Nimer, S.; more...
    Blood (2014)

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