Synapse - Marc Ladanyi

Results (59)

Exceptional responders with invasive mucinous adenocarcinomas: A phase 2 trial of bortezomib in patients with KRAS G12D-mutant lung cancers

Journal Article

Drilon, A.; Schoenfeld, A. J.; Arbour, K. C.; Litvak, A.; Ni, A.; Montecalvo, J.; Yu, H. A.; Panora, E.; Ahn, L.; Kennedy, M.; more...
Cold Spring Harbor Molecular Case Studies (2019)

Fulltext@MSK | Save

MDM2 amplification (Amp) to mediate cabozantinib resistance in patients (Pts) with advanced RET-rearranged lung cancers

Meeting Abstract

Somwar, R.; Smith, R.; Hayashi, T.; Ishizawa, K.; Charen, A. S.; Khodos, I.; Mattar, M.; He, J.; Balasubramanian, S.; Stephens, P.; more...
Journal of Clinical Oncology (2016)

Fulltext@MSK | Save

Reliable detection of ALK gene fusions in lung cancers by hybrid capture-based next-generation sequencing: High concordance with ALK FISH and ALK IHC

Meeting Abstract

Yelensky, R.; Donahue, A.; Chalmers, Z.; Otto, G.; Nahas, M.; He, J.; Juhn, F.; Frampton, G.; Chmielecki, J.; Ross, J.; more...
Laboratory Investigation (2015)

Fulltext@MSK | Save

Reliable detection of ALK gene fusions in lung cancers by hybrid capture-based next-generation sequencing: High concordance with ALK FISH and ALK IHC

Meeting Abstract

Yelensky, R.; Donahue, A.; Chalmers, Z.; Otto, G.; Nahas, M.; He, J.; Juhn, F.; Frampton, G.; Chmielecki, J.; Ross, J.; more...
Modern Pathology (2015)

Fulltext@MSK | Save

Next-generation sequencing (NGS) to identify actionable genomic alterations (GA) in "pan-negative" lung adenocarcinomas (ADC) from patients with no smoking or a light smoking (NS/LS) history

Meeting Abstract

Drilon, A. E.; Wang, L.; Arcila, M. E.; Cho, E. J.; Balasubramanian, S.; Greenbowe, J. R.; Ross, J. S.; Stephens, P.; Lipson, D.; Miller, V. A.; more...
Journal of Clinical Oncology (2014)

Fulltext@MSK | Save

Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers

Journal Article

Yu, H. A.; Arcila, M. E.; Rekhtman, N.; Sima, C. S.; Zakowski, M. F.; Pao, W.; Kris, M. G.; Miller, V. A.; Ladanyi, M.; Riely, G. J.
Clinical Cancer Research (2013)

Fulltext@MSK | Save

RAS signaling pathway gene mutations and acquired resistance to EGFR tyrosine-kinase inhibitors in EGFR mutant lung cancer

Meeting Abstract

Ohashi, K.; Chmielecki, J.; Lin, Y. L.; Pan, H. L.; Vnencak-Jones, C.; Arcila, M.; Wang, L.; Fernandez, L.; Keisuke, A.; Shien, K.; more...
Cancer Research (2012)

Fulltext@MSK | Save

HER2 amplification: A potential mechanism of acquired resistance to egfr inhibition in EGFR -mutant lung cancers that lack the second-site EGFR T790M mutation

Journal Article

Takezawa, K.; Pirazzoli, V.; Arcila, M. E.; Nebhan, C. A.; Song, X.; de Stanchina, E.; Ohashi, K.; Janjigian, Y. Y.; Spitzler, P. J.; Melnick, M. A.; more...
Cancer Discovery (2012)

Fulltext@MSK | Save

Driver mutations determine survival in smokers and never-smokers with stage IIIB/IV lung adenocarcinomas

Journal Article

Paik, P. K.; Johnson, M. L.; D'Angelo, S. P.; Sima, C. S.; Ang, D.; Dogan, S.; Miller, V. A.; Ladanyi, M.; Kris, M. G.; Riely, G. J.
Cancer (2012)

Fulltext@MSK | Save

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

Journal Article

Zhang, Z.; Lee, J. C.; Lin, L.; Olivas, V.; Au, V.; Laframboise, T.; Abdel-Rahman, M.; Wang, X.; Levine, A. D.; Rho, J. K.; more...
Nature Genetics (2012)

Fulltext@MSK | Save