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David S Klimstra

  1. "Early Drug Development Service"
Formats
  1. Journal Article (10)
  2. Meeting Abstract (6)
Groups
  1. Department of Medicine (16)
  2. Department of Pathology and Laboratory Medicine (16)
  3. Early Drug Development Service (16)
  4. GSK Faculty (16)
  5. Human Oncology and Pathogenesis Program (16)
  6. Solid Tumor Oncology Division (16)

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People
  1. David Hyman (16)
  2. Michael Berger (15)
  3. Ahmet Zehir (14)
  4. David Solit (13)
  5. Marc Ladanyi (10)
  6. Leonard Saltz (9)

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Years
  1. 2020 (1)
  2. 2019 (3)
  3. 2018 (1)
  4. 2017 (6)
  5. 2016 (3)
  6. 2015 (2)
Publications
  1. Journal of Clinical Oncology (6)
  2. Clinical Cancer Research (3)
  3. JAMA Oncology (2)
  4. American Journal of Surgical Pathology (1)
  5. Annals of Oncology (1)
  6. Cancer Research (1)

More Publications

Publishers
  1. American Society of Clinical Oncology (6)
  2. American Association for Cancer Research (4)
  3. American Medical Association (3)
  4. Lippincott Williams & Wilkins (1)
  5. Nature Publishing Group (1)
  6. Oxford University Press (1)

Results (16)

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  • Development of genome-derived tumor type prediction to inform clinical cancer care
    Journal Article

    Penson, A.; Camacho, N.; Zheng, Y.; Varghese, A. M.; Al-Ahmadie, H.; Razavi, P.; Chandarlapaty, S.; Vallejo, C. E.; Vakiani, E.; Gilewski, T.; more...
    JAMA Oncology (2020)

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  • Clinical validation of a genomics-based classifier to predict tissue of origin from targeted tumor sequencing
    Meeting Abstract

    Zheng, Y.; Penson, A. V.; Camacho, N.; Biederstedt, E.; Zehir, A.; Kandoth, C.; Syed, A.; Varghese, A. M.; Al-Ahmadie, H. A.; Schultz, N.; more...
    Cancer Research (2019)

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  • Prospective genotyping of hepatocellular carcinoma: Clinical implications of next-generation sequencing for matching patients to targeted and immune therapies
    Journal Article

    Harding, J. J.; Nandakumar, S.; Armenia, J.; Khalil, D. N.; Albano, M.; Ly, M.; Shia, J.; Hechtman, J. F.; Kundra, R.; El Dika, I.; more...
    Clinical Cancer Research (2019)

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  • Microsatellite instability is associated with the presence of Lynch syndrome pan-cancer
    Journal Article

    Latham, A.; Srinivasan, P.; Kemel, Y.; Shia, J.; Bandlamudi, C.; Mandelker, D.; Middha, S.; Hechtman, J.; Zehir, A.; Dubard-Gault, M.; more...
    Journal of Clinical Oncology (2019)

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  • Comprehensive molecular profiling of intrahepatic and extrahepatic cholangiocarcinomas: Potential targets for intervention
    Journal Article

    Lowery, M. A.; Ptashkin, R.; Jordan, E.; Berger, M. F.; Zehir, A.; Capanu, M.; Kemeny, N. E.; O'Reilly, E. M.; El-Dika, I.; Jarnagin, W. R.; more...
    Clinical Cancer Research (2018)

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  • A prospective analysis of germline alterations (GA) in biliary tract cancer (BTC)
    Meeting Abstract

    Lowery, M. A.; Jordan, E.; Kemel, Y.; Mukherjee, S.; Cercek, A.; Kemeny, N. E.; Varghese, A. M.; Rusek, M.; Boucher, T. M.; Mandelker, D.; more...
    Journal of Clinical Oncology (2017)

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  • Clinical and molecular characterization of patients with cancer of unknown primary in the modern era
    Journal Article

    Varghese, A. M.; Arora, A.; Capanu, M.; Camacho, N.; Won, H. H.; Zehir, A.; Gao, J.; Chakravarty, D.; Schultz, N.; Klimstra, D. S.; more...
    Annals of Oncology (2017)

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  • Real-time genomic profiling of pancreatic ductal adenocarcinoma: Potential actionability and correlation with clinical phenotype
    Journal Article

    Lowery, M. A.; Jordan, E. J.; Basturk, O.; Ptashkin, R. N.; Zehir, A.; Berger, M. F.; Leach, T.; Herbst, B.; Askan, G.; Maynard, H.; more...
    Clinical Cancer Research (2017)

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  • Pan-TRK immunohistochemistry is an efficient and reliable screen for the detection of NTRK fusions
    Journal Article

    Hechtman, J. F.; Benayed, R.; Hyman, D. M.; Drilon, A.; Zehir, A.; Frosina, D.; Arcila, M. E.; Dogan, S.; Klimstra, D. S.; Ladanyi, M.; more...
    American Journal of Surgical Pathology (2017)

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  • Mutation detection in patients with advanced cancer by universal sequencing of cancer-related genes in tumor and normal DNA vs guideline-based germline testing
    Journal Article

    Mandelker, D.; Zhang, L.; Kemel, Y.; Stadler, Z. K.; Joseph, V.; Zehir, A.; Pradhan, N.; Arnold, A.; Walsh, M. F.; Li, Y.; more...
    JAMA - Journal of the American Medical Association (2017)

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