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Adriana Haimovitz-Friedman

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Kinase suppressor of Ras transphosphorylates c-Raf-1

Journal Article

Zafrullah, M.; Yin, X.; Haimovitz-Friedman, A.; Fuks, Z.; Kolesnick, R.
Biochemical and Biophysical Research Communications (2009)

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A ceramide-binding C1 domain mediates kinase suppressor of Ras membrane translocation

Journal Article

Yin, X.; Zafrullah, M.; Lee, H.; Haimovitz-Friedman, A.; Fuks, Z.; Kolesnick, R.
Cellular Physiology and Biochemistry (2009)

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PKCα activation downregulates ATM and radio-sensitizes androgen-sensitive human prostate cancer cells in vitro and in vivo

Journal Article

Truman, J. P.; Rotenberg, S. A.; Kang, J. H.; Lerman, G.; Fuks, Z.; Kolesnick, R.; Marquez, V. E.; Haimovitz-Friedman, A.
Cancer Biology and Therapy (2009)

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Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

Journal Article

Coward, J.; Ambrosini, G.; Musi, E.; Truman, J. P.; Haimovitz-Friedman, A.; Allegood, J. C.; Wang, E.; Merrill, A. H. Jr; Schwartz, G. K.
Autophagy (2009)

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A ceramide rheostat balances angiogenesis and anti-angiogenesis

Meeting Abstract

Truman, J. P.; Garcia-Barros, M.; Hambardzumyan, D.; Stancevic, B.; Hicklin, D. J.; Fuks, Z.; Kolesnick, R.; Haimovitz-Friedman, A.
Cancer Research (2008)

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Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa

Journal Article

Rotolo, J. A.; Maj, J. G.; Feldman, R.; Ren, D.; Haimovitz-Friedman, A.; Cordon-Cardo, C.; Cheng, E. H. Y.; Kolesnick, R.; Fuks, Z.
International Journal of Radiation Oncology, Biology, Physics (2008)

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Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities

Journal Article

Duan, D.; Sigano, D. M.; Kelley, J. A.; Lai, C. C.; Lewin, N. E.; Kedei, N.; Peach, M. L.; Lee, J.; Abeyweera, T. P.; Rotenberg, S. A.; more...
Journal of Medicinal Chemistry (2008)

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Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans

Journal Article

Deng, X.; Yin, X.; Allan, R.; Lu, D. D.; Maurer, C. W.; Haimovitz-Friedman, A.; Fuks, Z.; Shaham, S.; Kolesnick, R.
Science (2008)

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The role of membrane lipid rafts in the response to ionizing radiation

Meeting Abstract

Zhang, J.; Rotolo, J. A.; Stancevic, B.; Donepudi, M.; Haimovitz-Friedman, A.; Fuks, Z.; Kolesnick, R. N.
Cancer Research (2007)

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Anti-angiogenic treatment regulates endothelial cell death via acid sphingomyelinase activation

Meeting Abstract

Truman, J. P.; Hambardzumyan, D.; Garcia-Barros, M.; Hicklin, D. J.; Kolesnick, R.; Fuks, Z.; Haimovitz-Friedman, A.
Cancer Research (2007)

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