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Stewart H Shuman

Results (108)

Clutch mechanism of chemomechanical coupling in a DNA resecting motor nuclease

Journal Article

Unciuleac, M. C.; Meir, A.; Xue, C.; Warren, G. M.; Greene, E. C.; Shuman, S.
Proceedings of the National Academy of Sciences of the United States of America (2021)

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Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22

Journal Article

Benjamin, B.; Sanchez, A. M.; Garg, A.; Schwer, B.; Shuman, S.
PLoS Genetics (2021)

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Pseudomonas putida MPE, a manganese-dependent endonuclease of the binuclear metallophosphoesterase superfamily, incises single-strand DNA in two orientations to yield a mixture of 3'-PO(4) and 3'-OH termini

Journal Article

Ghosh, S.; Ejaz, A.; Repeta, L.; Shuman, S.
Nucleic Acids Research (2021)

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A genetic screen for suppressors of hyper-repression of the fission yeast PHO regulon by Pol2 CTD mutation T4A implicates inositol 1-pyrophosphates as agonists of precocious lncRNA transcription termination

Journal Article

Garg, A.; Shuman, S.; Schwer, B.
Nucleic Acids Research (2020)

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Caveat mutator: Alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation

Journal Article

Unciuleac, M. C.; Goldgur, Y.; Shuman, S.
Nucleic Acids Research (2020)

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Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3' processing and transcription termination that functions via its effects on CTD phosphatase Ssu72

Journal Article

Sanchez, A. M.; Garg, A.; Shuman, S.; Schwer, B.
Nucleic Acids Research (2020)

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Mycobacterial DNA polymerase I: Activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme

Journal Article

Ghosh, S.; Goldgur, Y.; Shuman, S.
Nucleic Acids Research (2020)

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Substrate analogs that trap the 2′-phospho-ADP-ribosylated RNA intermediate of the Tpt1 (tRNA 2′-phosphotransferase) reaction pathway

Journal Article

Dantuluri, S.; Abdullahu, L.; Munir, A.; Katolik, A.; Damha, M. J.; Shuman, S.
RNA (2020)

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Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection

Journal Article

Jia, N.; Unciuleac, M. C.; Xue, C.; Greene, E. C.; Patel, D. J.; Shuman, S.
Proceedings of the National Academy of Sciences of the United States of America (2019)

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Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: Conformational switches in the kinase upon binding of the GTP phosphate donor

Journal Article

Banerjee, A.; Goldgur, Y.; Schwer, B.; Shuman, S.
Nucleic Acids Research (2019)

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