Synapse - William Pao

Results (17)

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

Journal Article

Veeriah, S.; Taylor, B. S.; Meng, S.; Fang, F.; Yilmaz, E.; Vivanco, I.; Janakiraman, M.; Schultz, N.; Hanrahan, A. J.; Pao, W.; more...
Nature Genetics (2010)

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EGFR T790M decreases growth potential of lung tumor cells with drug-sensitive EGFR mutant alleles in the absence of drug selection

Meeting Abstract

Chmielecki, J.; Foo, J.; Somwar, R.; Regales, L.; Vivanco, I.; Shen, R.; Michor, F.; Pao, W.
Cancer Research (2009)

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An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors

Journal Article

Chitale, D.; Gong, Y.; Taylor, B. S.; Broderick, S.; Brennan, C.; Somwar, R.; Golas, B.; Wang, L.; Motoi, N.; Szoke, J.; more...
Oncogene (2009)

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Acquired resistance to epidermal growth factor receptor (EGFR) kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma

Meeting Abstract

Bean, J.; Riely, G. J.; Balak, M.; Marks, J. L.; Ladanyi, M.; Miller, V. A.; Pao, W.
Journal of Clinical Oncology (2008)

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Mutations in the EGFR kinase domain mediate Stat3 activation via IL-6 production in human lung adenocarcinomas

Meeting Abstract

Gao, S. P.; Mark, K. G.; Leslie, K.; Pao, W.; Motoi, N.; Gerald, W. L.; Travis, W. D.; Bornmann, W.; Veach, D.; Clarkson, B.; more...
Cancer Research (2008)

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An integrated analysis of gene expression, copy number alterations, and kinase pathway mutations in lung adenocarcinoma reveals frequent loss of the MAPK phosphatase Gene DUSP4 in EGFR mutant tumors

Meeting Abstract

Chitale, D.; Gong, Y.; Broderick, S.; Brennan, C.; Taylor, B. S.; Somwar, R.; Wang, L.; Motoi, N.; Szoke, J.; Sander, C.; more...
Laboratory Investigation (2008)

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An integrated analysis of gene expression, copy number alterations, and kinase pathway mutations in lung adenocarcinoma reveals frequent loss of the MAPK phosphatase gene DUSP4 in EGFR mutant tumors

Meeting Abstract

Chitale, D.; Gong, Y.; Broderick, S.; Brennan, C.; Taylor, B. S.; Somwar, R.; Wang, L.; Motoi, N.; Szoke, J.; Sander, C.; more...
Modern Pathology (2008)

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Specific EGFR mutations predict treatment outcome of stage IIIB/IV patients with chemotherapy-naive non-small-cell lung cancer receiving first-line gefitinib monotherapy

Journal Article

Yang, C. H.; Yu, C. J.; Shih, J. Y.; Chang, Y. C.; Hu, F. C.; Tsai, M. C.; Chen, K. Y.; Lin, Z. Z.; Huang, C. J.; Shun, C. T.; more...
Journal of Clinical Oncology (2008)

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Genetic predictors of MEK dependence in non-small cell lung cancer

Journal Article

Pratilas, C. A.; Hanrahan, A. J.; Halilovic, E.; Persaud, Y.; Soh, J.; Chitale, D.; Shigematsu, H.; Yamamoto, H.; Sawai, A.; Janakiraman, M.; more...
Cancer Research (2008)

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Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma

Journal Article

Bean, J.; Riely, G. J.; Balak, M.; Marks, J. L.; Ladanyi, M.; Miller, V. A.; Pao, W.
Clinical Cancer Research (2008)

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