Synapse - Darren Veach

Results (99)

C-elegans ABL-1 functions similarly to Bcr-Abl and antagonizes p53-mediated germ cell apoptosis

Meeting Abstract

Deng, X.; Yin, X.; Veach, D. R.; Clarkson, B.; Bornmann, W. G.; Fuks, Z.; Kolesnick, R. N.
Cancer Research (2005)

BCR-ABL kinase dynamics in drug resistance

Meeting Abstract

Azam, M.; Nardi, V.; Shakespeare, W.; Latek, R. R.; Bohacek, R.; Veach, D.; Clarkson, B.; Sawyer, T. K.; Daley, G. Q.
Clinical Cancer Research (2005)

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BCR-ABL kinase dynamics and drug resistance

Meeting Abstract

Azam, M.; Nardi, V.; Shakespear, W. C.; Latek, R. R.; Veach, D.; Clarkson, B.; Bohacheck, R.; Sawyer, T. K.; Daley, G. Q.
Blood (2005)

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PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

Journal Article

Wolff, N. C.; Veach, D. R.; Tong, W. P.; Bornmann, W. G.; Clarkson, B.; Ilaria, R. L.
Blood (2005)

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A cell-based screen for resistance of Bcr-Abl-positive leukemia identifies the mutation pattern for PD166326, an alternative Abl kinase inhibitor

Journal Article

Von Bubnoff, N.; Veach, D. R.; Van Der Kuip, H.; Aulitzky, W. E.; Sanger, J.; Seipel, P.; Bornmann, W. G.; Peschel, C.; Clarkson, B.; Duyster, J.
Blood (2005)

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Synthesis and in vitro examination of [(124)I]-, [(125)I]- and [(131)I]-2-(4-iodophenylamino) pyrido[2,3-d]pyrimidin-7-one radiolabeled Abl kinase inhibitors

Journal Article

Veach, D. R.; Namavari, M.; Beresten, T.; Balatoni, J.; Minchenko, M.; Djaballah, H.; Finn, R. D.; Clarkson, B.; Gelovani, J. G.; Bornmann, W. G.; more...
Nuclear Medicine and Biology (2005)

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Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases

Journal Article

Reeves, P. M.; Bommarius, B.; Lebeis, S.; McNulty, S.; Christensen, J.; Swimm, A.; Chahroudi, A.; Chavan, R.; Feinberg, M. B.; Veach, D.; more...
Nature Medicine (2005)

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A cell-based screening method for resistance of Bcr-Abl positive leukemia identifies the mutation pattern for an alternative abl kinase inhibitor

Meeting Abstract

Von Bubnoff, N.; Veach, D. R.; Van Der Kuip, H.; Aulitzky, W. E.; Saenger, J.; Seipel, P.; Bornmann, W. G.; Peschel, C.; Clarkson, B.; Duyster, J.
Blood (2004)

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Efficacy of dual-specific Bcr-Abl and Src-family kinase inhibitors in cells sensitive and resistant to imatinib mesylate

Journal Article

Tipping, A. J.; Baluch, S.; Barnes, D. J.; Veach, D. R.; Clarkson, B.; Bornmann, W. G.; Mahon, F. X.; Goldman, J. M.; Melo, J. V.
Leukemia (2004)

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Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation

Journal Article

Deng, X.; Hofmann, E. R.; Villanueva, A.; Hobert, O.; Capodieci, P.; Veach, D. R.; Yin, X.; Campodonico, L.; Glekas, A.; Cordon-Cardo, C.; more...
Nature Genetics (2004)

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