Groups

Research Focus

Human Oncology and Pathogenesis Program; Research Scholar

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1. Pharmacological restoration of GTP hydrolysis by mutant RAS

   Journal Article

   Cuevas-Navarro, A.; Pourfarjam, Y.; Hu, F.; Rodriguez, D. J.; Vides, A.; Sang, B.; Fan, S.; Goldgur, Y.; de Stanchina, E.; Lito, P.
   Nature (2025)

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2. Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

   Journal Article

   Holderfield, M.; Lee, B. J.; Jiang, J.; Tomlinson, A.; Seamon, K. J.; Mira, A.; Patrucco, E.; Goodhart, G.; Dilly, J.; Gindin, Y.; more...
   Nature (2024)

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3. Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS

   Journal Article

   Schulze, C. J.; Seamon, K. J.; Zhao, Y.; Yang, Y. C.; Cregg, J.; Kim, D.; Tomlinson, A.; Choy, T. J.; Wang, Z.; Sang, B.; more...
   Science (2023)

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