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Research Focus

Former Employee. CHEMICAL BIOLOGY PROGRAM; Senior Research Scientist

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1. Optimized M24B aminopeptidase inhibitors for CARD8 inflammasome activation

   Journal Article

   Chen, Q.; Wang, A.; Covelli, D. J.; Bhattacharjee, A.; Wang, Q.; Orth-He, E. L.; Rao, S. D.; Huang, H. C.; Ball, D. P.; Hsiao, J. C.; more...
   Journal of Medicinal Chemistry (2023)

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2. Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation

   Journal Article

   Orth-He, E. L.; Huang, H. C.; Rao, S. D.; Wang, Q.; Chen, Q.; O'Mara, C. M.; Chui, A. J.; Saoi, M.; Griswold, A. R.; Bhattacharjee, A.; more...
   Cell Reports (2023)

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3. M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome

   Journal Article

   Rao, S. D.; Chen, Q.; Wang, Q.; Orth-He, E. L.; Saoi, M.; Griswold, A. R.; Bhattacharjee, A.; Ball, D. P.; Huang, H. C.; Chui, A. J.; more...
   Nature Chemical Biology (2022)

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