Research Focus

Former Employee. COMPUTATIONAL AND SYSTEMS BIOLOGY PROGRAM; Research Scholar

Recent additions – View all

1. Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding

   Journal Article

   Singh, S.; Gapsys, V.; Aldeghi, M.; Schaller, D.; Rangwala, A. M.; White, J. B.; Bluck, J. P.; Scheen, J.; Glass, W. G.; Guo, J.; more...
   Journal of Physical Chemistry B (2025)

   Fulltext@MSK | Save
2. INK4 tumor suppressor proteins mediate resistance to CDK4/6 kinase inhibitors

   Journal Article

   Li, Q.; Jiang, B.; Guo, J.; Shao, H.; Del Priore, I. S.; Chang, Q.; Kudo, R.; Li, Z.; Razavi, P.; Liu, B.; more...
   Cancer Discovery (2022)

   Fulltext@MSK | Save
3. Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance

   Journal Article

   Lyczek, A.; Berger, B. T.; Rangwala, A. M.; Paung, Y.; Tom, J.; Philipose, H.; Guo, J.; Albanese, S. K.; Robers, M. B.; Knapp, S.; more...
   Proceedings of the National Academy of Sciences of the United States of America (2021)

   Fulltext@MSK | Save