Synapse - Parvathy Manoj

Results (35)

SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing

Journal Article

Redin, E.; Sridhar, H.; Zhan, Y. A.; Mello, B. P.; Zhong, H.; Durani, V.; Sabet, A.; Manoj, P.; Linkov, I.; Qiu, J.; more...
Journal of Hematology & Oncology (2024)

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Identifying early and late hallmarks of plasticity in neuroendocrine transformation of lung cancer at single-cell level

Meeting Abstract

Chan, J. M.; Quintanal-Villalonga, A.; Sabet, A.; Manoj, P.; Masilionis, I.; Falcon, C.; Sohail, N.; Chun, J.; Nawy, T.; Mazutis, L.; more...
Journal of Thoracic Oncology (2023)

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Exportin 1 inhibition constraints lineage plasticity and histological transformation through downregulation of SOX2

Meeting Abstract

Quintanal-Villalonga, A.; Durani, V.; Sabet, A.; Redin, E.; Kawasaki, K.; Shaffer, M.; Manoj, P.; Sridhar, H.; Haffner, M. C.; Sawyers, C. L.; more...
Journal of Thoracic Oncology (2023)

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De novo and histologically transformed small-cell lung cancer is sensitive to lurbinectedin treatment through the modulation of EMT and NOTCH signaling pathways

Journal Article

Chakraborty, S.; Coleman, C.; Manoj, P.; Demircioglu, D.; Shah, N.; de Stanchina, E.; Rudin, C. M.; Hasson, D.; Sen, T.
Clinical Cancer Research (2023)

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Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers

Journal Article

Quintanal-Villalonga, A.; Durani, V.; Sabet, A.; Redin, E.; Kawasaki, K.; Shafer, M.; Karthaus, W. R.; Zaidi, S.; Zhan, Y. A.; Manoj, P.; more...
Science Translational Medicine (2023)

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Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies

Journal Article

Glasner, A.; Rose, S. A.; Sharma, R.; Gudjonson, H.; Chu, T.; Green, J. A.; Rampersaud, S.; Valdez, I. K.; Andretta, E. S.; Dhillon, B. S.; more...
Nature Immunology (2023)

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Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade

Journal Article

Pai, J. A.; Hellmann, M. D.; Sauter, J. L.; Mattar, M.; Rizvi, H.; Woo, H. J.; Shah, N.; Nguyen, E. M.; Uddin, F. Z.; Quintanal-Villalonga, A.; more...
Cancer Cell (2023)

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The ectonucleotidase CD39 identifies tumor-reactive CD8(+) T cells predictive of immune checkpoint blockade efficacy in human lung cancer

Journal Article

Chow, A.; Uddin, F. Z.; Liu, M.; Dobrin, A.; Nabet, B. Y.; Mangarin, L.; Lavin, Y.; Rizvi, H.; Tischfield, S. E.; Quintanal-Villalonga, A.; more...
Immunity (2023)

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Ferroptosis evasion as a therapeutic strategy in STK11/KEAP1 co-mutant lung adenocarcinoma

Meeting Abstract

Durani, V.; Wohlhieter, C. A.; Quintanal-Villalonga, A.; Sen, T.; Manoj, P.; Rudin, C. M.
Cancer Research (2022)

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Exportin 1 inhibition as a therapeutic strategy for small cell lung cancer

Meeting Abstract

Quintanal-Villalonga, A.; Taniguchi, H.; Hao, Y.; Chow, A.; Zhan, Y. A.; Uddin, F.; Allaj, V.; Manoj, P.; Shah, N. S.; Bhanot, U. K.; more...
Cancer Research (2022)

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