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Research Focus

Former Employee. MOLECULAR BIOLOGY; Research Fellow

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1. Intratumoral TREX1 induction promotes immune evasion by limiting type I IFN

   Journal Article

   Toufektchan, E.; Dananberg, A.; Striepen, J.; Hickling, J. H.; Shim, A.; Chen, Y.; Nichols, A.; Paez, M. A. D.; Mohr, L.; Bakhoum, S. F.; more...
   Cancer Immunology Research (2024)

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2. ER-directed TREX1 limits cGAS activation at micronuclei

   Journal Article

   Mohr, L.; Toufektchan, E.; von Morgen, P.; Chu, K.; Kapoor, A.; Maciejowski, J.
   Molecular Cell (2021)

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3. cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing

   Journal Article

   Zhou, W.; Mohr, L.; Maciejowski, J.; Kranzusch, P. J.
   Molecular Cell (2021)

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