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Samir Zaidi

  1. "Human Oncology and Pathogenesis Program"
Formats
  1. Meeting Abstract (9)
  2. Journal Article (6)
Groups
  1. Department of Medicine (15)
  2. GME, Medicine (15)
  3. GSK Faculty (15)
  4. Graduate Medical Education (15)
  5. Hematology-Oncology Fellows (15)
  6. Human Oncology and Pathogenesis Program (15)

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People
  1. Charles Sawyers (11)
  2. Wouter Karthaus (10)
  3. Joseph Chan (9)
  4. Dana Pe'er (7)
  5. Jimmy Zhao (7)
  6. Anuradha Gopalan (6)

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Years
  1. 2025 (1)
  2. 2024 (5)
  3. 2023 (3)
  4. 2022 (4)
  5. 2020 (2)
Publications
  1. Journal of Clinical Oncology (4)
  2. Cancer Research (3)
  3. Annals of Oncology (1)
  4. European Journal of Cancer (1)
  5. Nature Cancer (1)
  6. Proceedings of the National Academy of Sciences of the United States of America (1)

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Publishers
  1. American Society of Clinical Oncology (4)
  2. American Association for Cancer Research (3)
  3. American Association for the Advancement of Science (2)
  4. Springer Nature (2)
  5. Elsevier Inc. (1)
  6. National Academy of Sciences (1)

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Results (15)

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  • A phase 1b/2 study evaluating the activity of tinengotinib in combination with androgen receptor pathway inhibitors (ARPIs) in patients with metastatic castration resistant prostate cancer (mCRPC)
    Meeting Abstract

    Abida, W.; Chen, Y.; McHugh, D. J.; Morris, M. J.; Wu, F.; Peng, P.; Hennessy, K.; Wang, H.; Fan, J.; Zaidi, S.
    Journal of Clinical Oncology (2025)

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  • The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1
    Journal Article

    Romero, R.; Chu, T.; González Robles, T. J.; Smith, P.; Xie, Y.; Kaur, H.; Yoder, S.; Zhao, H.; Mao, C.; Kang, W.; more...
    Nature Cancer (2024)

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  • Effect of CDC7 inhibition and MYC degradation on neuroendocrine transformation in the lung and prostate cancer
    Meeting Abstract

    Quintanal-Villalonga, A.; Kawasaki, K.; Redin, E.; Rakhade, S.; Durani, V.; Sabet, A.; Karthaus, W.; Zaidi, S.; Zhan, Y. A.; Manoj, P.; more...
    Journal of Clinical Oncology (2024)

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  • CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation
    Journal Article

    Quintanal-Villalonga, A.; Kawasaki, K.; Redin, E.; Uddin, F.; Rakhade, S.; Durani, V.; Sabet, A.; Shafer, M.; Karthaus, W. R.; Zaidi, S.; more...
    Signal Transduction and Targeted Therapy (2024)

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  • Single-cell analysis of treatment-resistant prostate cancer: Implications of cell state changes for cell surface antigen–targeted therapies
    Journal Article

    Zaidi, S.; Park, J.; Chan, J. M.; Roudier, M. P.; Zhao, J. L.; Gopalan, A.; Wadosky, K. M.; Patel, R. A.; Sayar, E.; Karthaus, W. R.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2024)

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  • Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates
    Journal Article

    Ajkunic, A.; Sayar, E.; Roudier, M. P.; Patel, R. A.; Coleman, I. M.; De Sarkar, N.; Hanratty, B.; Adil, M.; Zhao, J.; Zaidi, S.; more...
    npj Precision Oncology (2024)

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  • CDC7 inhibition constrains lineage plasticity and prevents resistance and neuroendocrine transformation in the lung and prostate
    Meeting Abstract

    Quintanal-Villalonga, Á.; Zaidi, S.; Karthaus, W. R.; Zhan, Y. A.; Shafer, M.; Qiu, J.; de Stanchina, E.; Haffner, M. C.; Sawyers, C. L.; Rudin, C. M.
    Annals of Oncology (2023)

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  • Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers
    Journal Article

    Quintanal-Villalonga, A.; Durani, V.; Sabet, A.; Redin, E.; Kawasaki, K.; Shafer, M.; Karthaus, W. R.; Zaidi, S.; Zhan, Y. A.; Manoj, P.; more...
    Science Translational Medicine (2023)

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  • Effect of Janus kinase (JAK) signaling inhibition on lineage plasticity and drug sensitivity in castrate resistant prostate cancer
    Meeting Abstract

    Zaidi, S.; Chan, J. M.; Love, J.; Zhao, J.; Setty, M.; Lawrence, K.; Gopalan, A.; Goodrich, D.; Morris, M. J.; Chen, Y.; more...
    Journal of Clinical Oncology (2023)

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  • Multilineage plasticity in prostate cancer through expansion of stem-like luminal epithelial cells with elevated inflammatory signaling
    Meeting Abstract

    Zaidi, S.; Zhao, J.; Chan, J.; Martine, R.; Wadosky, K.; Gopalan, A.; Karthaus, W.; Watson, P.; True, L.; Nelson, P.; more...
    Cancer Research (2022)

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