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Taha Merghoub

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Journal Article (14)
  2. Meeting Abstract (11)
Groups
  1. Department of Medicine (25)
  2. GSK Faculty (25)
  3. Melanoma and Immunotherapeutics Service (25)
  4. Molecular Pharmacology and Chemistry Program Faculty (25)
  5. Sloan Kettering Institute Faculty (25)
  6. Solid Tumor Oncology Division (25)

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People
  1. Jedd Wolchok (17)
  2. Neal Rosen (13)
  3. Ronald Blasberg (8)
  4. Sadna Budhu (7)
  5. David Solit (6)
  6. Inna Serganova (6)

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Years
  1. 2023 (2)
  2. 2022 (4)
  3. 2021 (3)
  4. 2020 (4)
  5. 2019 (1)
  6. 2017 (2)

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Publications
  1. Cancer Research (5)
  2. Journal for ImmunoTherapy of Cancer (4)
  3. Cancer Immunology Research (2)
  4. Nature (2)
  5. Cancer Cell (1)
  6. Cancer Discovery (1)

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Publishers
  1. American Association for Cancer Research (8)
  2. Biomed Central Ltd (4)
  3. Nature Publishing Group (3)
  4. Cell Press (2)
  5. American Society of Clinical Oncology (1)
  6. Elsevier Science, Inc. (1)

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Results (25)

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  • Impact of tumor metabolism on the microenvironment and response to immunotherapy
    Meeting Abstract

    Zappasodi, R.; Serganova, I.; Brunschvig, S.; Santhella, A.; Mane, M.; Vemuri, K.; Ijoma, J.; Kang, W.; Manovatodorova, K.; Koutcher, J.; more...
    Cancer Science (2023)

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  • The ectonucleotidase CD39 identifies tumor-reactive CD8(+) T cells predictive of immune checkpoint blockade efficacy in human lung cancer
    Journal Article

    Chow, A.; Uddin, F. Z.; Liu, M.; Dobrin, A.; Nabet, B. Y.; Mangarin, L.; Lavin, Y.; Rizvi, H.; Tischfield, S. E.; Quintanal-Villalonga, A.; more...
    Immunity (2023)

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  • LDH inhibition improves response to CTLA-4 blockade by enhancing effector T cell activity and impairing regulatory T cell suppression
    Meeting Abstract

    Verma, S.; Serganova, I.; Budhu, S.; Dong, L.; Mangarin, L.; Ko, M.; Blasberg, R.; Zappasodi, R.; Wolchok, J.; Merghoub, T.
    Journal for ImmunoTherapy of Cancer (2022)

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  • Combining a novel MEK inhibitor with immunomodulation to promote an anti-tumor response
    Meeting Abstract

    Dong, L.; Choi, H.; Budhu, S.; Schulze, I.; Verma, S.; Mehanna, N.; Rosen, N.; Merghoub, T.; Wolchok, J.
    Cancer Research (2022)

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  • Deferiprone alters macrophage function and metabolism
    Meeting Abstract

    Ackerstaff, E.; Budhu, S.; Winkleman, D. P.; Min, S. S.; Ijoma, J. N.; Serganova, I. S.; Blasberg, R. G.; Merghoub, T.; Koutcher, J. A.
    Cancer Research (2022)

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  • Neoantigen quality predicts immunoediting in survivors of pancreatic cancer
    Journal Article

    Łuksza, M.; Sethna, Z. M.; Rojas, L. A.; Lihm, J.; Bravi, B.; Elhanati, Y.; Soares, K.; Amisaki, M.; Dobrin, A.; Hoyos, D.; more...
    Nature (2022)

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  • Combining a novel dual RAF/MEK inhibitor with immunomodulation to promote an anti-tumor response
    Meeting Abstract

    Dong, L.; Choi, H.; Budhu, S.; Schulze, I.; Mehanna, N.; Rosen, N.; Merghoub, T.; Wolchok, J.
    Journal for ImmunoTherapy of Cancer (2021)

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  • Pharmacologic modulation of tumor glycolysis to improve responses to immune checkpoint blockade therapy
    Meeting Abstract

    Verma, S.; Maniyar, R.; Ko, M.; Budhu, S.; Serganova, I.; Zappasodi, R.; Blasberg, R.; Merghoub, T.; Wolchok, J.; Mangarin, L.
    Journal for ImmunoTherapy of Cancer (2021)

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  • CTLA-4 blockade drives loss of T(reg) stability in glycolysis-low tumours
    Journal Article

    Zappasodi, R.; Serganova, I.; Cohen, I. J.; Maeda, M.; Shindo, M.; Senbabaoglu, Y.; Watson, M. J.; Leftin, A.; Maniyar, R.; Verma, S.; more...
    Nature (2021)

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  • CTLA-4 blockade promotes Treg glucose metabolism and reduces Treg functional stability in glycolysis-defective tumors
    Meeting Abstract

    Zappasodi, R.; Serganova, I.; Cohen, I.; Maeda, M.; Senbabaoglu, Y.; Shindo, M.; Maniyar, R.; Mane, M.; Leftin, A.; Watson, M.; more...
    Journal for ImmunoTherapy of Cancer (2020)

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